Clinical Trials Logo
  1. Home
  2. Central Sensitisation
  3. NCT06139120

The Segmental Distribution of Hypersensitivity in Patients With Chronic Subacromial Pain Syndrome

Central Sensitisation Clinical Trial

Official title:
Evaluation of the Segmental Distribution of Pain Hypersensitivity Among Patients With Central Sensitization Associated With Chronic Subacromial Pain Syndrome

Clinical Trial Summary

This study aimed to determine the distribution of pain sensitivity according to body segments in patients with central sensitization associated with chronic subacromial pain syndrome (SPS).This cross-sectional study included patients with chronic SPS and central sensitization (patient group) and the same number of healthy participants as controls. The presence of central sensitization was determined using the Central Sensitization Inventory. To determine the segmental distribution of pain sensitivity, pressure pain threshold measurements were performed bilaterally from the shoulder, forearm, and leg.

Clinical Trial Description

Shoulder pain is a common musculoskeletal pain condition in the general population, with a prevalence that has doubled in all age groups over the past 40 years, reaching 22%-30%. Despite treatment, at least 40% of patients report incomplete improvement in pain severity and duration of symptoms, which are the two main determinants of treatment response. There is convincing evidence that the persistence of pain in these patients is due to peripheral or central sensitization mechanisms. Central sensitization refers to pain hypersensitivity mainly resulting from amplifying central nervous system signals and reduced activity of central inhibitory pathways. The clinical presence of central sensitization is determined by examining specific pain characteristics or evaluating changes in pain threshold. The objective manifestation of central sensitization is a decreased pressure-pain threshold (PPT) (hypersensitivity). In previous studies using PPT measurement, pain sensitivity was detected in the shoulder and remote joints in patients with subacromial pain syndrome (SPS), which was considered as evidence of central sensitization. However, these studies did not show how pain sensitivity differs according to body segment in patients with SPS. Hypersensitivity that develops due to chronic shoulder pain would exacerbate the perception of pain caused by other musculoskeletal diseases or trauma. Therefore, it may be important for clinicians to determine how pain sensitivity varies by body segment in patients with SPS ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06139120
Study type Observational [Patient Registry]
Source Cukurova University
Contact
Status Completed
Phase
Start date September 20, 2022
Completion date December 30, 2022
View Details
See also
  Status Clinical Trial Phase
Completed NCT05062694 - Physical Therapy Management Of The Patient With Central Sensitization
Not yet recruiting NCT05986513 - Brain MRI for Knee OA N/A
Not yet recruiting NCT04542798 - CRF vs WCRF or PRF-DRG in CLBP of FJ Origin and RFA Failure of MBDR: Central Sensitization and Aberrant Nerve Sprouting N/A
Completed NCT05559021 - What Concept of Manual Therapy is More Effective? N/A
Completed NCT04485078 - Investigation of Central Sensitization Frequency and Related Factors in Axial Spondyloarthritis Patients
Completed NCT05162664 - Presence of Signs of Central Sensitization in Episodic and Chronic Migraine N/A
Recruiting NCT06043141 - Investigation of the Relationship Between Pain Sensitization and Diagnostic Parameters in Carpal Tunnel Syndrome
Completed NCT06336278 - Relationship Between Central Sensitization and Kinesiophobia in Knee Osteoarthritis
Terminated NCT05022251 - Identifying Pain Generators and Potentiators of Residual Complaints Following Lumbar Discectomy
Completed NCT04361149 - Motor Unit Abnormalities After Experimentally Induced Sensitization Phase 4
Completed NCT05146960 - Relation Between Temporal Summation and Fatigue N/A
Completed NCT04043962 - Mechanisms Of Change in Adolescent Pain Self-management N/A
Completed NCT03863808 - Effect of Cognitive Behavioral Therapy on Chronic Low Back Pain With Sensitization N/A
Active, not recruiting NCT05169918 - Sensorial Discrimination in Chronic Low Back Pain N/A
Completed NCT03531385 - Assessment of Central Sensitization, Neuropathic Pain, Sleep Quality and Daily Life Activities in Behcet's Disease
Recruiting NCT06169917 - Pain Processing In Relation To Breathing N/A
Not yet recruiting NCT06367998 - Effect of Pregabalin on Shoulder Pain in Patients With Central Sensitization After Arthroscopic Rotator Cuff Repair Phase 4
Completed NCT05932433 - Effectiveness of Therapeutic Exercise on the Gut Microbiome in Chronic Widespread Pain Patients. N/A
Completed NCT05381012 - Fibromyalgia Syndrome on Patients With Chronic Migraine N/A
Completed NCT05031286 - Differences in Pain Processing Between Men and Women N/A