Radio/Pathological Evaluation of Tongue Cancer Infiltration

Cell Carcinoma Clinical Trial

— RaP E ToC  

Official title:

An Evaluation of the Radio/Pathological Correlation of Depth Of Invasion for Oral Squamous Cell Carcinoma, a Retrospective Study in a University Hospital in Lyon

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04821128
• Other study ID #: 242
• Status: Recruiting
• Start date: November 27, 2020
• Est. completion date: May 27, 2021

Study information

• Verified date: March 2021
• Source: Hospices Civils de Lyon
• Contact: Leonard MEGUERDITCHIAN, MD
• Phone: 6 10 46 17 70
• Email: leonard.meguerditchian-hoffmeyer[@]chu-lyon.fr
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The aim of the study is to assess the good correlation and prediction of the DOI for the post-operative pathological results and prognosis.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 200
• Est. completion date: May 27, 2021
• Est. primary completion date: November 27, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• patients chirurgically treated for an OSCC
• T1 T2 T3
• CT scanner in their medical file

Exclusion Criteria:

• T4
• R+ résection
• Artefacts on CT scanner

Related Conditions & MeSH terms

• Carcinoma
• Cell Carcinoma
• Oral Squamous

Intervention

Other:
• Radiologic and pathological review.
We will analyse the pre operative scannographic and MRI (if available) images, and the post operative pathological analyses. The scanners will be reviewed by 2 well trained clinicians (one head and neck radiologist and one head and neck surgeon). Then we will analyse the correlation between the radiological and the pathological analysis.

Locations

Country	Name	City	State
France	Croix rousse hospital	Lyon

Sponsors (1)

Lead Sponsor	Collaborator
Hospices Civils de Lyon

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The primary outcome will be the measure of the correlation of the depth of invasion on the radiological pre operative images and of the pathological analyses on the resection piece.	With a Bland Altman analysis we will assess the good correlation between the pre and post operatory mesures of the depth of invasion in the oral squamous cell carcioma	The outcome will be measured at the inclusion of the patient in the current study.