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Safety and Effectiveness of Novel Nitroglycerin Based Catheter Lock Solution

Catheter-Related Infections Clinical Trial

Official title:
Phase 1/2 Study to Evaluate the Safety and Effectiveness of Novel Non-Antibiotic, Non-Heparin Nitroglycerin Based Catheter Lock Solution Used for the Prevention of Intraluminal Central Venous Catheter (CVC) Infections in Cancer Patients

Clinical Trial Summary

The objective of this Phase I/II pilot study is to evaluate the safety and effectiveness of a non- antibiotic chelator based lock solution that contains nitroglycerin in combination with sodium citrate and ethanol (NiCE lock solution) for prevention of central line associated bloodstream infection (CLABSI).

- The primary objective of this study is to evaluate the safety and estimate the rate of adverse events associated with the NiCE lock solution.

- The second primary objective is to estimate the rate of CLABSI in patients receiving the NiCE lock solution.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02577718
Study type Interventional
Source Novel Anti-Infective Technologies, LLC
Contact
Status Completed
Phase Phase 1/Phase 2
Start date November 2015
Completion date October 2016
View Details
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