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Catheter-Related Infections clinical trials

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NCT ID: NCT06095076 Recruiting - Dysbiosis Clinical Trials

Cutaneous Microbiota Evolution in ICU Patients With CVC (ICMc)

ICMc
Start date: June 2, 2023
Phase:
Study type: Observational

Intensive Care Unit (ICU) patients are exposed to catheter-related infections with an important morbidity. Catheter colonization is constant but infection is not. Cutaneous dysbiosis could be the missing link. Our study aims to evaluate the evolution of cutaneous microbiota in ICU patients with a central venous catheter in place, through metagenomics. Our main objective is to evaluate the evolution of alpha-diversity, quantified by intra-patient variation of Shannon diversity index (a diversity index used in bacterial metagenomics).

NCT ID: NCT05995080 Recruiting - Clinical trials for Catheter-Related Infections

The Effectiveness of Chlorhexidine Gluconate on Prevention of Catheter-Related Bloodstream Infections

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

Catheter-related bloodstream infections are associated with increased mortality, morbidity, and length of hospital stay. The incidence has decreased significantly with the strict implementation of preventive bundle cares and checklists in intensive care units. Bathing with solutions containing chlorhexidine has been included in preventive strategies in recent years. Although some studies have shown that chlorhexidine bathing reduces the frequency of hospital-associated infections, there are important differences in management of practice and adherence to practice in different facilities. The majority of the studies conducted include adult patients. According to the CDC guidelines, chlorhexidine bathing is recommended for children over 2 months of age to prevent catheter-related bloodstream infection. The aim of this study is to investigate the effect of daily bathing with 2% chlorhexidine gluconate solution in preventing catheter-related bloodstream infections in pediatric patients with temporary central venous catheters.

NCT ID: NCT05741866 Recruiting - Wound Infection Clinical Trials

Novel Antimicrobial Dressing in Peripheral Intravenous Catheters (PIVCs)

ProP
Start date: May 3, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare a chlorhexidine impregnated dressing for peripheral intravenous catheters (PIVCs) to the standard dressing currently used in general medical and surgical inpatient wards. The main questions it aims to answer are: - Study Feasibility - Occurrence of infectious complications related to the PIVC Participants will be randomly allocated to receive either of the below dressings to cover and secure their PIVC: - The standard dressing used at their hospital, or - The intervention dressing which has Chlorhexidine gluconate (CHG) on it Researchers will compare standard and CHG dressings to see if the presence of CHG improves the occurrence of infectious complications related to the PIVC.

NCT ID: NCT05670119 Recruiting - Clinical trials for Infection Control Training

The Effect of Catheter-Associated Infection Control Training

Start date: January 25, 2023
Phase: N/A
Study type: Interventional

The goal of this type of study: clinical trial is to determine the effectiveness of educational practices on catheter-associated infection control measures on surgical nurses. The main question it aims to answer are: - Is there a difference between the knowledge and attitude levels of surgical nurses receiving and not receiving catheter-related infection control training on preventing peripheral and central catheter-related bloodstream infections? - Is there a difference between the knowledge and attitude levels of surgical nurses receiving and not receiving catheter-related infection control training to prevent catheter-related urinary tract infections? The main tasks that the participants will be asked to do will be explained and their consent will be obtained. The two research groups will be compared.

NCT ID: NCT05495646 Recruiting - Clinical trials for Catheter-Related Infections

Infection Related to Short-term Central Venous Catheters

Start date: August 8, 2022
Phase:
Study type: Observational

This study aims to evaluate the incidence of infection of short-term central venous catheters by comparing different cannulation techniques (by anatomical references and under ultrasound control) and according to the experience of the operator in patients undergoing elective surgery. A prospective observational study will be carried out in which all scheduled surgery patients who have a central venous line inserted for 12 months will be included. Those under 18 years of age, patients with catheters lasting more than 14 days and those who do not sign the informed consent will be excluded from this study. A chest X-ray will be performed on all patients in order to diagnose possible complications associated with the technique and, only in case of suspected infection, culture of the catheter tip and blood cultures of blood obtained from the catheter and peripheral blood will be requested.

NCT ID: NCT04825314 Recruiting - Infection Clinical Trials

Noble Meta Alloy Coated Catheters in Patients With Long Term Catheterization

Start date: May 21, 2020
Phase: N/A
Study type: Interventional

Eighty percent of nosocomial UTI caused by indwelling urinary catheters and so known-as catheter-associated UTI. CAUTI leads to multiple local and systemic derangements such as suprapubic pain, dysuria, cystitis, pyelonephritis, septicemia, and even septic shock. This study will be conducted up on 100 patients (50 per each group) with long term catheterization to assess efficacy of noble metal alloy coated catheter in reducing CAUTI.

NCT ID: NCT04499638 Recruiting - Clinical trials for Diabetes Mellitus, Type 2

Incidence of Complications of Peripheral Venous Access in the Type 2 Diabetic Population

Start date: January 1, 2020
Phase:
Study type: Observational [Patient Registry]

Diabetes Mellitus type 2 (T2DM) is one of the most frequent metabolic diseases worldwide. It is expected that in 2035 around 600 million people will suffer from the disease. A recent systematic review has estimated that the direct annual cost of Diabetes worldwide treatments and care is over $ 827 billion and has been independently associated with nosocomial complications, thrombosis-like infections and prolonged admissions. In addition, it is estimated that up to 90% of patients in acute hospitals require a peripheral venous catheter which are associated at the same time with mechanical, infectious and thrombotic acute complications. Recently the emergence of new medium-sized peripheral devices (Midline®) and new peripheral central venous access catheters (PICC), which are more biocompatible, are opening new clinical possibilities with the aim of improving safety and comfort during treatment time and the reduction of associated complications. With all this, a observational case-control study has been proposed in order to analyze the impact of T2DM disease and its associated complications on the patient requiring peripheral venous access. Furthermore investigators will consider if these new peripheral devices can be a remarkable benefit for these patients. This study will be carried out at the Vall d'Hebron University Hospital in Barcelona, Spain

NCT ID: NCT04140916 Recruiting - Clinical trials for Catheter-Related Infections

Comparison of Two Peripheral Inserted Intravenous Catheters

Start date: October 7, 2018
Phase: N/A
Study type: Interventional

Central venous catheters are routinely used, however, with a complication rate exceeding 15%. Therefore, other types of venous catheters have been introduced such as a midline catheter. The purpose of the present study is to assess the efficacy and the safety of midline catheters compared to the standard care being a central catheter also inserted peripherally. Patients with indication for intravenous fluids or medicines for 5 to 28 days will be included in the study.

NCT ID: NCT03108079 Recruiting - Clinical trials for Urinary Incontinence

Bladder Morphology Using 2 Different Catheter Designs

Start date: April 2017
Phase: N/A
Study type: Interventional

Demonstrate and compare the 3D morphology of the bladder wall in full and drained states with 2 different kinds of bladder catheters in place. (Foley Catheter vs. Cystosure Catheter)

NCT ID: NCT02950246 Recruiting - Clinical trials for Catheter Related Infection

Alcoholic Chlorhexidine Compared to Povidone Iodine to Limit Perineural Catheter Colonisation

CHLOVEPI
Start date: November 2016
Phase: N/A
Study type: Interventional

Implementation of perineural catheters may lead to infection by catheter colonization. Catheters may be colonized by the bacteria present on the skin. This is most often commensal organisms as Staphylococcus or gram negative bacilli. In a large study of 1416 peripheral nerve catheters, 28.7% of catheters were cultured positive. This colonization is most often silent because in the same study only 3% of patients had signs of local inflammation and one psoas abscess was observed (0.07%). The germs are most often coagulase negative staphylococci (61%) and gram negative bacillus (21.6%).