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Catheter Infection clinical trials

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NCT ID: NCT06332040 Recruiting - Catheter Infection Clinical Trials

Gentamicin Bladder Instillation on CAUTI

Start date: October 9, 2023
Phase: Phase 4
Study type: Interventional

Urinary tract infections in catheterized patients is an unacceptable complication and has been termed a 'never event' by the Center for Medicare & Medicaid Services (CMS); however there is not consensus among clinicians on how to best prevent CAUTIs. We propose a prospective randomized controlled trial to test the efficacy of prophylactic gentamicin bladder irrigation in elimination of CAUTIs.

NCT ID: NCT05931887 Recruiting - Clinical trials for Catheter Related Complication

Evaluation of the Novel Silq ClearTract Catheter in Patients With Chronic Urinary Retention

Start date: July 26, 2023
Phase: N/A
Study type: Interventional

To assess the ability of the Silq ClearTractâ„¢ 100% Silicone 2-Way Foley Catheter to reduce catheter associated complications in subjects that require a long-term indwelling Foley catheter when compared to other commercially available Foley catheters.

NCT ID: NCT05741866 Recruiting - Wound Infection Clinical Trials

Novel Antimicrobial Dressing in Peripheral Intravenous Catheters (PIVCs)

ProP
Start date: May 3, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare a chlorhexidine impregnated dressing for peripheral intravenous catheters (PIVCs) to the standard dressing currently used in general medical and surgical inpatient wards. The main questions it aims to answer are: - Study Feasibility - Occurrence of infectious complications related to the PIVC Participants will be randomly allocated to receive either of the below dressings to cover and secure their PIVC: - The standard dressing used at their hospital, or - The intervention dressing which has Chlorhexidine gluconate (CHG) on it Researchers will compare standard and CHG dressings to see if the presence of CHG improves the occurrence of infectious complications related to the PIVC.

NCT ID: NCT05729321 Recruiting - Preterm Clinical Trials

Lock sOlutiOnS for Epicutaneo-caval Catheters in Neonates: a "LOOSEN" Pilot Study

LOOSEN
Start date: September 1, 2022
Phase:
Study type: Observational [Patient Registry]

Epicutaneo-caval catheters (ECCs) are widely used in neonatal intensive care units (NICUs). They are small catheters inserted via superficial veins of the limbs or scalp using direct vein visualization The pathogenic microorganisms colonized inside catheters can easily form a bacterial biofilm and eventually spread with blood flow which causes bloodstream infection. Many authors have studied the antibiotic-lock therapy (ALT) in which a high-dose antibiotic solution is dripped and maintained in the catheter cavity for a certain period and can dissolve the biofilm formed on the wall to reduce the colonization of the bacteria and kill the embedded bacteria.The aim of the study is to evaluate the patency of the Epicutaneo-caval catheter after its closure for 1 hour.

NCT ID: NCT05440396 Recruiting - Catheter Infection Clinical Trials

Identifying Local Signs at the Catheter Insertion Site With Artificial Intelligence

DeepCath
Start date: September 1, 2022
Phase:
Study type: Observational [Patient Registry]

Deepcath is the first step to the introduction of artificial intelligence in catheter care. A better use of visualisation of catheter exit site should be used not only by the HCWs but also by the patients and their family. A deep learning system able to detect visual abnormalities of the catheter exit site will be an helpful tools to develop a continuous follow-up of intravascular catheters.

NCT ID: NCT04825314 Recruiting - Infection Clinical Trials

Noble Meta Alloy Coated Catheters in Patients With Long Term Catheterization

Start date: May 21, 2020
Phase: N/A
Study type: Interventional

Eighty percent of nosocomial UTI caused by indwelling urinary catheters and so known-as catheter-associated UTI. CAUTI leads to multiple local and systemic derangements such as suprapubic pain, dysuria, cystitis, pyelonephritis, septicemia, and even septic shock. This study will be conducted up on 100 patients (50 per each group) with long term catheterization to assess efficacy of noble metal alloy coated catheter in reducing CAUTI.

NCT ID: NCT04548713 Recruiting - Clinical trials for Catheter Complications

CLiCK in the Critical Care Unit

CLiCK
Start date: March 22, 2022
Phase: N/A
Study type: Interventional

Insertion of a central venous access device (CVAD) allows clinicians to easily access the circulation of a patient to administer life-saving interventions. Due to their invasive nature, CVADss are prone to complications such as infection, bacterial biofilm production, and catheter occlusion due to a thrombus. A CVAD is placed in up to 97% of patients in the intensive care unit, exposing this vulnerable population to risk of nosocomial infection and occlusion. Current standard of care involves use of normal saline (for CVCs and PICCs) or citrate (for hemodialysis catheters) as a catheter locking solution. CVAD complications remain a problem with current standard of care. 4% tetrasodium Ethylenediaminetetraacetic acid (EDTA) fluid (KiteLock Sterile Locking Solution) possesses antimicrobial, anti-biofilm, and anti-thrombotic properties and is approved by Health Canada as a catheter locking solution. As such, it may be superior CVC locking solution than the present normal saline or citrate lock. To our knowledge, the efficacy of an EDTA catheter locking solution has not yet been investigated in the intensive care patient population. Our team proposes to fill this knowledge gap by performing a multi-centre, cluster-randomized, crossover study evaluating the impact of KiteLock Sterile Locking Solution on a primary composite outcome of CLABSI, intraluminal occlusion, and alteplase use in the ICU of six ICU's compared to the standard of care saline lock.

NCT ID: NCT03897959 Recruiting - Catheter Infection Clinical Trials

COMPARISON OF KOHLI AND FOLEY CATHETERS IN SUPRAPUBIC CATHETER PATIENTS

Start date: March 3, 2019
Phase: N/A
Study type: Interventional

The purpose of this medical research study is to compare two different urinary drainage catheters to see which has fewer problems with blockages and pain. The study involves completing 16 weekly 3-question surveys either online or by phone. The new catheters are FDA-approved and will be provided for FREE. No medications will be given.