Catheter-Related Infections Clinical Trial
Official title:
Phase 1/2 Study to Evaluate the Safety and Effectiveness of Novel Non-Antibiotic, Non-Heparin Nitroglycerin Based Catheter Lock Solution Used for the Prevention of Intraluminal Central Venous Catheter (CVC) Infections in Cancer Patients
The objective of this Phase I/II pilot study is to evaluate the safety and effectiveness of a
non- antibiotic chelator based lock solution that contains nitroglycerin in combination with
sodium citrate and ethanol (NiCE lock solution) for prevention of central line associated
bloodstream infection (CLABSI).
- The primary objective of this study is to evaluate the safety and estimate the rate of
adverse events associated with the NiCE lock solution.
- The second primary objective is to estimate the rate of CLABSI in patients receiving the
NiCE lock solution.
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