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Cataract clinical trials

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NCT ID: NCT05065749 Active, not recruiting - Cataract Clinical Trials

Clinical Results of Asqelio Trifocal Diffractive Intraocular Lens

Start date: March 7, 2022
Phase:
Study type: Observational

The study aims to evaluate the clinical outcomes six months after implantation of the trifocal diffractive intraocular lens Asqelio Trifocal IOL TFLIO130C in healthy subjects submitted to non-traumatic cataract surgery. This clinical performance will be assessed in terms of refractive error, visual performance at different distances, incidence of adverse events and complications following implantation, and patient satisfaction.

NCT ID: NCT05064189 Completed - Eye Diseases Clinical Trials

Protection of Corneal Epithelium Using Chitosan-N-acetylcysteine Eye Drops During and/or After Cataract Surgery

Start date: April 14, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to assess if treatment with Lacrimera® eye drops (Croma-Pharma GbmH, Leobendorf, Austria) during and/ or after cataract surgery has a positive effect on the ocular surface compared to control group.

NCT ID: NCT05062564 Completed - Cataract Clinical Trials

Efficacy of LipiFlow in Patients Affected by Meibomian Gland Dysfunction in Reducing Post-cataract Surgery Dry Eye

LIPICAT
Start date: September 7, 2021
Phase: N/A
Study type: Interventional

Dry Eye Disease (DED) is a disease of the ocular surface which may be secondary to a variety of causes, including cataract surgery. DED is characterized by loss of tear film stability and dry eye symptoms, and its pathogenesis is related to corneal nerve injury, decreased goblet cells, inflammation of the ocular surface, and dysfunction of the meibomian glands (MGD). MGD is the main cause of evaporative DED and can cause irregularity of the ocular surface, affecting the accuracy of the biometric calculation. In addition, it is a risk factor for DED exacerbation after cataract surgery, that may occur in about 40% of cases. Current therapies for DED include artificial tears, warm compresses, manual squeezing of the glands, eyelid hygiene, omega-3 fatty acids, topical cyclosporine, serum tears, topical azithromycin, oral doxycycline. The above therapies in some cases can provide only transient relief, affecting the outcome of cataract surgery and the quality of life of patients. Therefore, stabilization of the ocular surface before cataract surgery is important to achieve better post-operative comfort and a better refractive result. The introduction of LipiFlow thermal pulsation treatment (LTP) represents a controlled method of squeezing the obstructed Meibomian glands by applying heat to the upper and lower eyelids and simultaneously applying pulsatile pressure to the eyelid skin surfaces. The aim of our study will be to evaluate the effect of preoperative LipiFlow therapy in patients with age-related cataracts and mild to moderate MGD in reducing postoperative DED.

NCT ID: NCT05058274 Completed - Astigmatism Clinical Trials

Clinical Results of a Monofocal Aspheric Bitoric Intraocular Lens With Plate Haptics in Hyperopic Eyes (HIPER-AT-TORBI)

HIPER-AT-TORBI
Start date: November 3, 2021
Phase:
Study type: Observational

Observational post-marketing study with prospective follow-up of CE marked medical devices aimed at the treatment of hyperopia and astigmatism in patients with cataract. The objective is to evaluate the clinical results of the implantation of the monofocal aspheric bitoric intraocular lens (IOL) with AT-TORBI 709 plate haptics in cataract surgery of hyperopic eyes with astigmatism.

NCT ID: NCT05056233 Completed - Cataract Clinical Trials

Systane Hydration in Subjects Undergoing Cataract Surgery

Start date: January 18, 2022
Phase: N/A
Study type: Interventional

The primary objective of this study is to demonstrate reduced corneal staining with use of Systane Hydration among subjects with dry eye disease (DED) undergoing routine cataract removal and monofocal intraocular lens (IOL) implantation.

NCT ID: NCT05055076 Completed - Cataract Clinical Trials

PMCF Retrospective Study Outcomes of a Monofocal Toric Intraocular Lens

Start date: August 1, 2021
Phase:
Study type: Observational

This is a monocentric retrospective, open-label clinical study in patients after unilateral or bilateral implantation of hydrophobic acrylic monofocal toric intraocular lens PODEYE TORIC and executed only with standard of care examinations. The investigational device is CE approved. The investigational device and all study products, including the devices used for the study examinations, have been used within the intended use specifications from the manufacturer. In addition, there were no invasive or other burdening examinations. The investigator is an accredited and experienced cataract surgeon and researcher. The primary endpoint is to determine rotational stability in a minimum of 120 eyes of patients with PODEYE TORIC IOL implantation after cataract surgery. Patients will be enrolled for the documentation and evaluation of retrospective data up to 6 months postoperatively.

NCT ID: NCT05053620 Completed - Cataract Clinical Trials

Astigmatism Correction With Intrastromal Arcuate Incisions in Eyes Undergoing Cataract Surgery With Femtosecond Laser Using the Cassini Ambient With Iris Registration (ARCUATAS)

ARCUATAS
Start date: October 19, 2021
Phase:
Study type: Observational

This is an observational, prospective follow-up post-marketing study of CE marked medical devices aimed at treating astigmatism in patients with cataracts. The main objective is to evaluate the response of the intrastromal arcuate incisions procedure for the correction of low corneal astigmatism with the Catalys femtosecond laser using the Cassini Ambient equipment with iris registration in cataract surgery.

NCT ID: NCT05053399 Completed - Cataracts Clinical Trials

Evaluation of the TECNIS Symfony® Toric Intraocular Lens

Start date: November 24, 2021
Phase: N/A
Study type: Interventional

This is a prospective, single-center, single-arm, open-label, clinical study of the investigational TECNIS Symfony® Toric IOL. The study will enroll up to 100 subjects from a single investigative site in China. The subjects will be followed for 12-months postoperatively.

NCT ID: NCT05049629 Terminated - Eye Diseases Clinical Trials

Effect of Chitosan-N-Acetylcysteine on IOL-power Prior to Cataract Surgery

Start date: May 12, 2021
Phase: N/A
Study type: Interventional

Aim of this study is to evaluate the effect of treatment with Lacrimera® on calculated IOL power prior to cataract surgery and on the stability of ocular surface parameters compared to preservative-free, Hyaluronic-acid containing eyedrops (Hylo-Vision® sine).

NCT ID: NCT05042856 Not yet recruiting - Cataract Clinical Trials

To Evaluate IOL Position, Clinical Outcome of PanOptix in High Myopic Cataract Patients

Start date: October 1, 2021
Phase: N/A
Study type: Interventional

To evaluate IOL position, clinical outcome of PanOptix in high myopic cataract patients