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Cataract clinical trials

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NCT ID: NCT03740659 Completed - Cataract Clinical Trials

Evaluation Of Aqueous Humor Of Levofloxacin-Dexamethasone Eye Drops And Of Its Components In Patients Undergoing Cataract Surgery

iPERME
Start date: September 4, 2018
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the penetration of levofloxacin and dexamethasone 21-phosphate into the aqueous humour after ocular administration in combination or as single active ingredients.

NCT ID: NCT03739528 Completed - Cataract Clinical Trials

Levo-Dexa vs. Tobra+Dexa for Prevention and Treatment of Inflammation and Prevention of Infection in Cataract Surgery

LEADER7
Start date: September 3, 2018
Phase: Phase 3
Study type: Interventional

The purpose of this study is to demonstrate the non-inferiority of the study treatment (combined levofloxacin + dexamethasone eye drops) followed by dexamethasone eye drops alone vs. standard treatment in the prevention and treatment of postoperative ocular inflammation and prevention of infection.

NCT ID: NCT03735368 Completed - Conscious Sedation Clinical Trials

Dexmedetomidine and Pregabalin for Conscious Sedation During Cataract Surgery

Start date: December 10, 2018
Phase: Phase 2
Study type: Interventional

Although topical anesthesia by eye drops for cataract surgery is a non-invasive technique but it may provide insufficient anesthesia which requires the intraoperative use of additional topical local anesthetics and raises the need for sedation.

NCT ID: NCT03729024 Completed - Cataract Clinical Trials

Exploratory Study to Evaluate Uncorrected Distance Vision and Quality of Vision After Light Treatments of an Implanted RxSight Light Adjustable Lens (RXLAL) With The Light Delivery Device (LDD) in Subjects With Preoperative Corneal Astigmatism

Start date: January 26, 2018
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate uncorrected distance vision and quality of vision as measured by the McAlinden QoV questionnaire 3 months following the final lock-in treatment of the implanted RxSight Light Adjustable Lens (RxLAL) with the Light Delivery Device (LDD) in subjects with preoperative keratometric astigmatism. This is an exploratory study. No primary effectiveness endpoints will be defined.

NCT ID: NCT03708367 Completed - Cataracts Clinical Trials

A Post-Market Evaluation of LipiFlow Treatment in Cataract Surgery Practice

Start date: October 16, 2018
Phase: N/A
Study type: Interventional

This is a post-market, prospective, randomized, multi-center, bilateral, open-label, cross-over, comparative clinical study. Study group will undergo preoperative LipiFlow treatment and Control group will not receive preoperative LipiFlow treatment. Three months postoperatively, both groups will be evaluated for clinical outcomes and the Control group will receive LipiFlow treatment as the cross-over group. The Control group will be evaluated at 4 months postoperative for clinical outcomes.

NCT ID: NCT03706066 Completed - Cataract Clinical Trials

India PanOptix Post Marketing Study

Start date: January 15, 2019
Phase:
Study type: Observational

The purpose of this Post Marketing Study is to study the safety and effectiveness of the ACRYSOF IQ PanOptix intraocular lens (IOL) in an Indian population.

NCT ID: NCT03705949 Completed - Cataract Clinical Trials

Impact of 0.1% and 0.2% Sodium Hyaluronate on Postoperative Discomfort Following Phacoemulsification Surgery

Start date: September 15, 2017
Phase: N/A
Study type: Interventional

Primary objective of the study is the assessment of the patients' discomfort following cataract extraction surgery by means of phacoemulsification and intraocular lens implantation.

NCT ID: NCT03693989 Completed - Cataract Clinical Trials

Clinical Study of the Efficacy of the Ophthalmic Emulsion PRO-145 for Inflammation and Pain After Phacoemulsification

PRO-145/III
Start date: October 4, 2018
Phase: Phase 3
Study type: Interventional

objective: To evaluate the efficacy of the ophthalmic emulsion PRO-145 in the treatment of inflammation and pain after phacoemulsification. Hypothesis: The use of the ophthalmic emulsion PRO-145 is effective in decreasing the inflammatory response evaluated by means of cellularity in the anterior chamber, after phacoemulsification. Methodology: Phase III clinical trial, double-blind, controlled, parallel group, multicentre, randomized. Number of patients: 178 subjects divided into 2 groups (89 subjects per group), who will provide an eye for the evaluation of efficacy. Diagnosis and main inclusion criteria: Diagnosis: Postoperative phacoemulsification and foldable intraocular lens placement in a bag.

NCT ID: NCT03692728 Completed - Childhood Cataract Clinical Trials

Increased Risk of ADHD Among Children With Bilateral Congenital Cataracts

Start date: July 1, 2016
Phase:
Study type: Observational

In this study, the investigators conducted a cross-sectional, face-to-face investigation to evaluate the behavioral and psychological disorders and the risk of ADHD among children with bilateral congenital cataracts using the Conners'Parent Rating Scale (CPRS) questionnaire, an assessment tool for screening ADHD that obtains parental reports of childhood behavioral problems in research and clinical settings.15-17 Age-matched children with normal vision and the Chinese urban norm were used as controls.

NCT ID: NCT03689270 Completed - Cataract Clinical Trials

Corneal Edema After Phacoemulsification

COPHA
Start date: January 2015
Phase:
Study type: Observational

To compare the impact of two phacoemulsification techniques (subluxation versus divide-and-conquer) on postoperative corneal edema at postoperative hour 1 and day 4.