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Cataract clinical trials

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NCT ID: NCT04682288 Completed - Cataract Clinical Trials

Levofloxacin Ocular Implant for Ocular Surgery

Start date: January 4, 2021
Phase: Phase 1
Study type: Interventional

This is a multi center, open label, interventional study in one eye of 5 subjects scheduled for uncomplicated cataract surgery with administration of a single Levofloxacin Ocular Implant in the posterior sulcus of the surgical eye at the end of cataract surgery.

NCT ID: NCT04676451 Completed - Cataract Clinical Trials

Femtosecond Laser Assisted Keratotomies for the Management of Corneal Astigmatism

Start date: May 14, 2018
Phase: N/A
Study type: Interventional

A cataract is a clouding of the lens that occurs naturally with age. Cataract surgery involves removal of the cloudy lens and replacement with an artificial one. A special laser (femtosecond laser) is now being used to help make cataract surgery safer and more accurate . The femtosecond laser can also be used to correct astigmatism, an irregular curvature of the cornea, at the time of cataract surgery through a procedure called astigmatic keratotomy (AK). This study is gathering information about the specific laser settings that are used to perform astigmatic keratotomies (AK) during cataract surgery. This information will be used to improve the outcomes of patients that receive cataract surgery with astigmatic keratotomies in the future.

NCT ID: NCT04670575 Completed - Cataract Clinical Trials

Vivity Outcomes in Patients With Early Stage Glaucoma

VIVA
Start date: January 1, 2021
Phase:
Study type: Observational

The goal of the study is to determine the visual outcomes in patients with mild, pre-perimetric glaucoma who undergo cataract surgery with implantation of the Alcon Vivity Extended Range Intraocular Lens (IOL).

NCT ID: NCT04655274 Completed - Cataract Senile Clinical Trials

Comparision of Visual Outcomes and Patient Satisfaction Between Two Diffractive Trifocal Intraocular Lenses

Start date: November 30, 2020
Phase:
Study type: Observational

The purpose of the present study was to compare the clinical outcomes such as visual function, refraction errors and visual quality of patients undergoing cataract surgery with implantation of two different models of diffractive trifocal IOLs: RayOne Trifocal (Rayner IOL, Ltd.) and AcrySof IQ PanOptix (Alcon Laboratories, Inc.) IOL.

NCT ID: NCT04652037 Completed - Cataract Clinical Trials

Visual Results of the Acrysof IQ Vivity Toric Extended Vision Intraocular Lens

Start date: March 17, 2021
Phase: N/A
Study type: Interventional

The main goal of this study is to evaluate real-world visual outcomes, rotational stability, and patient reported visual disturbances with a non-diffractive extended vision presbyopia and astigmatism correcting intraocular lens in patients with significant corneal astigmatism undergoing bilateral cataract surgery. This is important to ensure optimal results for patients who wish to have intraocular lenses that correct presbyopia and astigmatism, thus giving them a greater independence from spectacles and a better quality of life.

NCT ID: NCT04633954 Completed - Cataract Surgery Clinical Trials

Brimonidine for Subconjunctival Hemorrhage From Femtosecond Laser Assisted Cataract Surgery

Start date: June 6, 2019
Phase: N/A
Study type: Interventional

Laser-assisted cataract surgery is a common and precise procedure done to remove cataracts from the eye. This procedure involves putting on a suction cup that applies a mild vacuum seal around the eye to stabilize the eye during the laser procedure. This suction cup often causes some bleeding under the conjunctiva around the eye which takes a few days to disappear. The purpose of this study is to test the use of a well-known eye medication (normally for treating glaucoma) called Brimonidine tartrate 0.15% (or Alphagan-P) in patients having laser-assisted cataract surgery. The use of Brimonidine to reduce bleeding under the conjunctiva is investigational, which means it has not been approved by Health Canada for use outside of research studies like this one. This study will see if Brimonidine will help to reduce bleeding under the conjunctiva in patients having laser-assisted cataract surgery.

NCT ID: NCT04631315 Completed - Cataract Clinical Trials

Difluprednate vs. a Prednisolone Acetate - Phenylephrine on Post-operative Inflammation Following Cataract Surgery.

Start date: March 24, 2019
Phase: Phase 4
Study type: Interventional

This controlled, randomized, double blind, multicenter study will be carried out to demonstrate that the topical ophthalmic nanoemulsion of difluprednate 0.05% (Tolf®, Poen Laboratories), has a high anti-inflammatory efficacy, which would allow it to be administered after cataract surgery 1 drop, twice a day , starting the day before surgery and continuing for 14 days and 1 drop, once a day for the following 2 weeks, achieving an adequate anti-inflammatory activity, with the benefit of reducing the toxicity on the ocular surface, improving the dosage and adherence to treatment. The follow-up time will be 28 days and the outcome measures will be evaluated in a baseline (time 0), on day 1, on day 4 and on day 28 after surgery. The active control will be prednisolone acetate 1% + phenylephrine hydrochloride 0.12% topical ophthalmic suspension (Prednefrin® Forte, Allergan Argentina) given 1 drop, 4 times a days and 1 drop, twice a day for the next 2 weeks. Corneal thickness, central macula thickness, endothelial cell count, intraocular pressure, visual acuity, anterior chamber clearance and lacrimal film recovery will be evaluated.

NCT ID: NCT04631068 Completed - Cataract Clinical Trials

Clinical Comparison of a Monofocal eDOF IOL With a Monofocal IOL

MonoeDOF
Start date: September 21, 2020
Phase: N/A
Study type: Interventional

Post-market, prospective, randomized, single-masked, multi-center clinical study investigating the safety and effectiveness of the Monofocal Extended Depth of Focus Intraocular Lens (Mono-EDoF IOL) when compared to a Standard Monofocal Intraocular Lens. Primary Objectives: - To evaluate the distance VA of the study IOLs - To evaluate the intermediate VA of the study IOLs - To explore the safety profile with regards to visual disturbances

NCT ID: NCT04630509 Completed - Traumatic Cataract Clinical Trials

Epidemiology and Outcome of Pediatric Traumatic Cataract

Start date: January 1, 2019
Phase:
Study type: Observational

this study aims to explore the demography of pediatric traumatic cataract in upper Egypt, and report outcomes and complications of traumatic cataract surgery in these children.

NCT ID: NCT04629521 Completed - Cataract Clinical Trials

Additional Long-Term Follow-up for Subjects Implanted With a CyPass® Micro-Stent

COMPASS XXT
Start date: December 21, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to assess long-term (10 years post-CyPass implantation) status of the corneal endothelium in subjects who were implanted with the CyPass Micro-Stent in the COMPASS trial.