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Cataract clinical trials

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NCT ID: NCT06015334 Not yet recruiting - Cataract Clinical Trials

Assessment of Visual Performance With Virtual Reality After Cataract Surgery

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

The proposed randomized clinical trial aims to compare visual performance, measured using VR simulations, in cataract patients implanted either with bilateral trifocal IOL or bilateral monofocal IOL with monovision. The hypothesis is that patients implanted with trifocal IOL would exhibit superior visual performance, in both daytime and nighttime conditions, compared to those with a monofocal IOL with monovision.

NCT ID: NCT06005675 Active, not recruiting - Cataracts Clinical Trials

User Acceptability Evaluation of Pseudophakic Patients Previously Implanted With the TECNIS Odyssey IOL

Start date: September 6, 2023
Phase:
Study type: Observational

Prospective collection of data from medical records, multicenter, post-market clinical follow-up study.

NCT ID: NCT06002399 Not yet recruiting - Cataract Clinical Trials

Bilateral Monofocal Versus Monofocal-EDOF IOL Implantation: Quality of Vision Comparison

COMEDI
Start date: November 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare visual quality after cataract surgery between two groups: bilateral monofocal intraocular lenses (IOL) and monofocal and contralateral extended depth-of-focus (EDOF) IOL implantation. The main question it aims to answer is: • does the combination of both monofocal and EDOF IOLs presents an advantage over bilateral monofocal IOL implantation in the daily life of patients undergoing cataract surgery without the disadvantages of bilateral EDOF IOL implantation? Participants will: - be randomised in either bilateral monofocal group or monofocal and EDOF group - undergo visual acuity testing with and without correction at all distances - be asked to complete a quality of vision questionnaire - undergo non-invasive examinations to measure residual astigmatism, contrast sensitivity, straylight, optical aberrations, reading spead.

NCT ID: NCT05992415 Not yet recruiting - Cataract Clinical Trials

New York City Eye Study (NYCES)

NYCES
Start date: July 1, 2024
Phase: N/A
Study type: Interventional

Dr. Lisa A. Hark (PI and Study Chair) and an interdisciplinary team have designed the New York City Eye Study (NYCES) to promote eye and vision health equity and address eye health disparities in adults age 21+ (PAR-23-009/NOT-EY-22-004).

NCT ID: NCT05991960 Completed - Cataracts Clinical Trials

Evaluation of Real-World Data on the Performance of the TECNIS Odyssey™ IOL

Start date: September 11, 2023
Phase:
Study type: Observational

Retrospective collection of data from medical records, multicenter, post-market clinical follow-up study.

NCT ID: NCT05990712 Not yet recruiting - Cataract Clinical Trials

The Effect of a Pre-cataract Surgical Ocular Hygiene Regime on Microbial Load, Tear Osmolarity, Dry Eye, and Inflammatory Markers

Start date: September 1, 2023
Phase: Phase 4
Study type: Interventional

This study assesses the impact of two differing ocular hygiene regimens prior to cataract surgery. The first regimen includes an omega-3 supplement and the second without, and both include an at-home lid wipe and cleansing eye drops. These regimens will be assessed on microbial load, inflammation, tear osmolarity, and dry eye metrics. Patients will be randomized to either the omega-3 group + 3-part hygiene regimen, or the group with only the 3-part hygiene regimen. Data will be collected for inflammation through a test (InflammaDry) that measures an inflammatory marker, dry eye metrics via an imaging tool called Oculus 5M and the Canadian Dry Eye Assessment (CDEA) questionnaire, tear osmolarity through Tear Labs device, and area of growth for conjunctiva microbial load by swabbing the conjunctiva of the eye. Dry eye metrics (CDEA and Oculus 5M) will be collected during the patient's baseline appointment, 2-5 days prior to surgery, and post-operative month 1. Microbial load swabs will be collected at baseline, 2-5 days prior to surgery, and date of the surgery. An ocular assessment will also be completed at baseline, one week post-operation, and one month post-operation. All metrics will be compared to the fellow eye. The usage of omega-3 will be compared to the regimen without omega-3.

NCT ID: NCT05988827 Recruiting - Cataract Clinical Trials

Effect of Minimizing Light Exposure Intensity on Macular Function After Cataract Surgery in Patients With Early or Intermediate AMD

EMERGING
Start date: September 14, 2023
Phase: N/A
Study type: Interventional

Cataract surgery is one of the most frequently performed surgical interventions worldwide. The microscope light-induced retinal toxicity after cataract surgery has been described in several reports even in short procedures; however, this potential toxicity has not been evaluated by objective criteria. Indeed, this retinal phototoxicity would be increased for patients with mild macular diseases such as early stages of AMD (Aged Macular Degeneration) (ie: drusen) which are frequently associated in elderly patients with cataract. The aim of the study will be to assess the potential functional macular effects by focal and multifocal ERG after cataract surgery with NGenuity by comparison to Standard Operating Microscope (SOM). This study would particularly address eyes at risk for macular toxicity like patients with early or intermediate AMD

NCT ID: NCT05980117 Not yet recruiting - Clinical trials for Cognitive Impairment

Remimazolam for Cataract Surgery

Start date: July 2024
Phase: Phase 4
Study type: Interventional

The goal of this study is to assess any post operative cognitive changes following benzodiazepine administration during cataract surgery. The investigators will compare effects of Midazolam vs. Remimazolam on cognition at the time of discharge from the post operative care unit and the next day following surgery. Cognitive changes will be assessed by administration of Montreal Cognitive Assessment (MoCA). Participants will: 1. Complete MoCA testing prior to surgery 2. Randomize in either Midazolam or study drug Remimazolam 3. Complete MoCA testing after surgery at the time of discharge in the post anesthesia care unit and the next day of surgery at the time of post operative surgical visit. 4. Complete Patient Satisfaction Survey at the time of discharge from the Post Anesthesia Care Unit (PACU)

NCT ID: NCT05961046 Terminated - Cataract Clinical Trials

Visual Performance of the Vivity IOL in Post-myopic LASIK and PRK Patients

Start date: August 17, 2023
Phase:
Study type: Observational

The objective is to evaluate visual outcomes and patient satisfaction in patients with a history of myopic LASIK or PRK who will have completed cataract surgery with the Vivity IOL.

NCT ID: NCT05958459 Not yet recruiting - Cataract Clinical Trials

The Effect of Eye Exercises on Visual Function and Quality of Life After Multifocal Intraocular Lens Implantation

Start date: August 4, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to examine the effects of eye exercises on visual function and quality of life in cataract patients undergoing multifocal intraocular lens implantation. The main questions it aims to answer are: - Does it improve visual functions? - Does it improve vision-related quality of life? Participants in the intervention group will perform 8-step eye exercises at least once a day for 12 weeks. The control group will not practice, they will only be evaluated.