ATTR Cardiac Amyloidosis in a Selected Population

Status Not yet recruiting

Clinical Trial Summary

Patients operated for carpal tunnel syndrome (CTS) at Ålesund Hospital (200 patients) will have a biopsy to diagnose ATTR amyloidosis. Patients with positive biopsy will be examined to decide wether they have cardiac amyloidosis. All patients with positive biopsy will be followed closely for 10 years wit echocardiography an clinically.

Clinical Trial Description

Biopsy proven ATTR (v/wt) amyloidosis inpatients operated with CTS will undergo standard guidelines recommended examinations as 99mTcDPD SPECT CT, echocardiography, ECG, Holter, genetic testing (v/wt), and lab testing, and CMRI as indicated. Exclusion of light chain disease will be done. All patients will be followed at least yearly as indicated by guidelines (ESC), and patients with development of cardiac amyloidosis will get standard treatment in accordance with guidelines and as approved by the Norwegian government. All patients will be followed for 10 years. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06458374
Study type	Observational
Source	Helse Møre og Romsdal HF
Contact
Status	Not yet recruiting
Phase
Start date	June 17, 2024
Completion date	February 28, 2039

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT05067205` - Minimal Invasive Carpal Tunnel Release With the Novel Device	N/A
Completed	`NCT03184688` - Platelet Rich Plasma for Carpal Tunnel Syndrome	N/A
Completed	`NCT03582735` - Preoperative Neuromobilization Exercises for Individuals With Carpal Tunnel Syndrome	N/A
Completed	`NCT05490420` - Effects of Upper Extremity Manual Lymphatic Drainage on Symptom Severity, Hand Functions, Electrophysiological and Ultrasonographic Measurements in Carpal Tunnel Syndrome	N/A
Recruiting	`NCT05970692` - Cross-Cultural Adaptation and Psychometric Validation of the Turkish Version of Atroshi-Lyrén 6-item Symptoms Scale
Completed	`NCT04043780` - Clinical Validation of a Decompression Prototype Splint for Patients With Carpal Tunel Syndrome	N/A
Completed	`NCT03880812` - Cost Information on Carpal Tunnel Syndrome Treatment Decisions	N/A
Completed	`NCT06464809` - Treatment Intervention of Patients With Carpal Tunnel Syndrome (CTS)	N/A
Recruiting	`NCT05503719` - An Absorbable Suture Versus a Non-absorbable Suture in Carpal Tunnel Release, a Randomized Controlled Trial	N/A
Recruiting	`NCT05328180` - aDjunct bicarbonatE in Local anaesthesIa for CarpAl Tunnel rElease (DELICATE)	N/A
Recruiting	`NCT05372393` - Carpal Tunnel Release Under Local Anaesthesia With or Without Distal Median Nerve Block	N/A
Recruiting	`NCT05466162` - Soft Tissue Massage Along With Mobilization Technique on Symptoms and Functional Status of Carpal Tunnel Syndrome	N/A
Completed	`NCT04060875` - Research Protocol for Karuna Labs Inc.: Safety and Efficacy of Virtual Reality Graded Motor Imagery for Chronic Pain
Not yet recruiting	`NCT06294821` - 4AP to Delay Carpal Tunnel Release (CTR)	Phase 2/Phase 3
Not yet recruiting	`NCT04328805` - Pain Reduction and Changes in Upper Limb Function Produced by an Ibuprofen Treatment in Carpal Tunnel Syndrome.	Phase 4
Terminated	`NCT02791529` - Scalpel Versus Electrocautery for Surgical Skin Incision in Open Carpal Tunnel Release	Phase 1
Completed	`NCT02141035` - Acetyl-l-carnitine to Enhance Nerve Regeneration in Carpal Tunnel Syndrome	Phase 2/Phase 3
Completed	`NCT01887145` - Comparison of Long-term Outcomes Following Endoscopic or Open Surgery for Carpal Tunnel Syndrome	N/A
Recruiting	`NCT01897272` - Post-Operative Splinting After Short-Incision Carpal Tunnel Release: a Prospective Study	N/A
Completed	`NCT01394822` - Neuromuscular Ultrasound for Focal Neuropathies	N/A