Effect of Neurodynamic Mobilization on Median Nerve Conduction Velocity in Carpal Tunnel Syndrome

Carpal Tunnel Syndrome Clinical Trial

Official title:

Effect of Neurodynamic Mobilization on Median Nerve Conduction Velocity in Carpal Tunnel Syndrome

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05788471
• Other study ID #: Raghda Ahmed_PhD
• Status: Not yet recruiting
• Phase: N/A
• Start date: April 1, 2023
• Est. completion date: August 15, 2023

Study information

• Verified date: March 2023
• Source: Cairo University
• Contact: Raghda Ahmed
• Phone: +201225615248
• Email: rodynody88[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to examine: 1. The effect of neurodynamic mobilization on the sensory and motor median nerve conduction velocity in carpal tunnel syndrome. 2. The effect of neurodynamic mobilization on the wrist pain in carpal tunnel syndrome. 3. The effect of neurodynamic mobilization on the hand function in carpal tunnel syndrome.

Description:

The findings of this study will provide physiotherapists with information to know if neurodynamic mobilization techniques is effective on median nerve conduction velocity in carpal tunnel syndrome also this will improve our body of knowledge about the best modalities for treating carpal tunnel syndrome. The finding of this study may help carpal tunnel syndrome patients to avoid the exposing to complications as a result of compression of median nerve in carpal tunnel syndrome.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 40
• Est. completion date: August 15, 2023
• Est. primary completion date: June 15, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 50 Years

Eligibility

Inclusion Criteria:

• Forty carpal tunnel syndrome patients.
• All participants referred from a physician.
• Their ages range from 20-50 years old.
• Both genders will participate in the study.
• Their BMI ranges between 18.5-24.9kg/m2.
• All participants have carpal tunnel syndrome at least in one hand.
• All participants suffering from mild to moderate carpal tunnel syndrome.

Exclusion Criteria:

• Previous or current disease or trauma that might affect one or both upper limbs.
• Metabolic diseases that might associated with entrapment neuropathy such as diabetes mellitus, thyroid diseases, and autoimmune diseases.
• Pregnant women.
• Participants with congenital hand deformities.
• History of hand surgery.
• Sever cases of carpal tunnel syndrome that suffering from weakness of hand grip and atrophy of thenar muscle.

Related Conditions & MeSH terms

• Carpal Tunnel Syndrome
• Median Neuropathy
• Nerve Compression Syndromes
• Syndrome

Intervention

Other:
• conventional Treatment
It consists of Superficial heat, Ultrasound therapy and stretching exercise to lumbrical muscles of the hand.
• Neurodynamic mobilization
It is the mobilisation of the nervous system as an approach to physical treatment of pain. The treatment and or assessment relies on influencing pain physiology via the mechanical treatment of neural tissues and non-neural structures surrounding the nervous system.

Locations

Country	Name	City	State
Egypt	Outpatient clinic faculty of physica therapy cairo university	Dokki

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Assessing the change in nerve conduction velocity of the median nerve.	By using Electromyography apparatus measuring nerve conduction velocity of the median nerve. (motor and sensory in m/s)	at baseline and after 4 weeks of intervention
Primary	Assessing the change in wrist joint pain	By using Pressure pain threshold (PPT) is defined as the minimal amount of pressure that produces pain. A simple handheld pressure algometer (PA) with a spring is commonly used, although more sophisticated electrical devices with a strain or pneumatic pressure gauge have been developed. They hold the peak force or pressure (kp (kilopond) = 10 N, Newton = 100 kPa (kilopascal)) until tared, and some may also be connected to a computer and thus have continuous output. PPT measured with a probe 1.6 mm in diameter or larger reflects the tenderness of deep tissues as anesthesia of skin only affects the results of smaller probes.	at baseline and after 4 weeks of intervention
Primary	Assessing the change in functional activity of the hand	By using Modified DASH questionnaire will be used for functional activity of the hand. The Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire is a 30-item questionnaire that looks at the ability of a patient to perform certain upper extremity activities. This questionnaire is a self-report questionnaire that patients can rate difficulty and interference with daily life on a 5 point Likert scale. The QuickDASH tool uses a 5-point Likert scale from which the patient can select an appropriate number corresponding to his/her severity/function level.	at baseline and after 4 weeks of intervention