Carpal Tunnel Syndrome Clinical Trial
Official title:
Effects of a Preoperative Neuromobilization Program Offered to Individuals With Carpal Tunnel Syndrome Awaiting Carpal Tunnel Release Surgery: a Pilot Randomized Controlled Trial
Carpal tunnel syndrome is one of the major known disorders of the wrist and hand that causes pain, tingling sensations, weakness of the hand and functional limitations in daily tasks (for example: handling objects with the hands). In the early stages of the syndrome, some individuals may benefit from wearing wrist splint or cortisone infiltration. For those with ongoing symptoms, surgery is often indicated. However, some individuals may experience worsening of their condition while waiting for surgery. To aid those individuals, physiotherapists often recommend exercises that aim to "glide" the nerve inside the arm. Specifically, these exercises involve arm and neck movements in a specific order, with the aim of improving the motion of the median nerve in relation with its environment. These nerve gliding exercises may have a favorable effect on the median nerve and may improve pain and upper limb functional abilities. In this study, the investigators aim to evaluated the feasibility and effects of a preoperative nerve gliding exercises completed by individuals undergoing surgery
Carpal Tunnel Syndrome (CTS) is a common disorder characterized by alterations of the median
nerve integrity at the carpal tunnel. The syndrome is classically recognized by chief
complains of nocturnal or intermittent pain and paresthesia involving the median nerve
sensory territory of the hand. In more severe condition, worsening of pain and paresthesia as
well as thenar muscle atrophy may be present and lead to disability.
Many conservative treatments for CTS are available. Yet, the current literature only support
the use of wrist splints and cortisone infiltration, which have been shown to provide only
temporary relief for many individuals. Those with ongoing symptoms or severe conditions are
often offered carpal tunnel decompression surgery. However, the costs related to the surgery
and the increasing delays on waiting lists warrants the need for better conservative
management. A preoperative rehabilitation exercise program based on nerve gliding exercise is
advocated by physical therapists to manage physical impairments and functional limitations
associated with CTS. These exercises can be implement at low cost in the setting of an
home-based program.
The investigators aim to examine the feasibility and the efficacy of a preoperative home
rehabilitation program based on nerve gliding exercises completed by individuals with carpal
tunnel Syndrome waiting for decompression surgery.
In this trial, individuals awaiting carpal tunnel decompression surgery will be randomly
allocated to either complete a preoperative nerve-gliding exercise program (experimental
group) or no intervention (control group). Thirty participants confirmed with CTS by their
attending hand surgeons and enlisted for carpal tunnel decompression will be recruited for
this study conducted at the hospital of the Université de Montréal (CHUM), Montreal, Quebec,
Canada. All individuals enrolled in the study will be prioritized on the surgical waiting
list to receive their surgery five weeks after initiating the study in order to ensure
consistency between different timeframes of the study.
The effects of the nerve-gliding exercise program will be assessed at baseline (T0) using
standardized questionnaires, quantitative ultrasound measurements (including static and
dynamic evaluations) of the median nerve, pinch grip strength and will be repeated after four
weeks (T1; preoperative period) and four weeks following surgery (T2; postoperative period).
Feasibility metrics will be analyzed using descriptive statistics. A significant interaction
between the group allocation (experimental vs. control) and time (T0 vs. T1 vs. T2) on the
main outcomes will be evaluated using two-way mixed ANOVAs.
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