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Carpal Tunnel Syndrome clinical trials

View clinical trials related to Carpal Tunnel Syndrome.

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NCT ID: NCT05405218 Completed - Clinical trials for Carpal Tunnel Syndrome

Trial of Ultrasound Guided Carpal Tunnel Release Versus Traditional Open Release (TUTOR)

TUTOR
Start date: July 26, 2022
Phase: N/A
Study type: Interventional

Study to compare the safety and effectiveness of carpal tunnel release with ultrasound guidance (CTR-US) vs. mini-open carpal tunnel release (mOCTR) in patients with symptomatic carpal tunnel syndrome (CTS).

NCT ID: NCT05394870 Completed - Clinical trials for Carpal Tunnel Syndrome

Clinical and Electrophysiological Evaluation of the Effectiveness for Manual Lymphatic Drainage

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

When the other usage areas of the manual lymphatic drainage technique in the literature, except for the treatment of lymphedema, were examined recently, it was seen that it was also applied in orthopedic and neurological cases in a limited number of studies. The aim of our study is to investigate the effectiveness of manual lymphatic drainage on clinical and electrophysiological findings in carpal tunnel syndrome

NCT ID: NCT05343351 Completed - Pain Clinical Trials

Effect of Out of Plane and In Plane Injection Techniques in Patients With Carpal Tunnel Syndrome

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

The aim of this study, using two different injection techniques, 1. To evaluate the patients in terms of the pain they feel during the application of carpal tunnel syndrome (CTS) injection, 2. Evaluation in terms of undesirable effects developing after injection, 3. To evaluate the degree of pain/drowsiness, symptom severity and functionality, and median nerve diameter at the end of the first month after the injection, and to evaluate the relationship of these parameters with the pain felt by the patients during the injection.

NCT ID: NCT05342870 Completed - Dexmedetomidine Clinical Trials

A Sequential Allocation Study to Determine the ED50 of Dexmetedomidine as an Adjuvant to Lidocaine Intravenous Regional Anesthesia

Start date: August 2012
Phase: N/A
Study type: Interventional

Intravenous Regional Anesthesia (IVRA) is an easy and reliable anesthetic technique for hand and forearm surgery. Its use is however limited by the presence of tourniquet pain during the surgery and the absence of postoperative analgesia. Many adjuvants to local anesthetics have been studied in order to overcome these shortcomings, including α2 adrenergic agonists. Clonidine has been shown to be efficacious when used with IVRA at a dose of 1µg/kg. Dexmetedomidine (DEX) is a recent more selective α2 adrenergic agonist that has been used successfully during IVRA at a dose of 0.5µg/kg. However when comparing potency ratios of Clonidine and DEX (8 to 1), the investigators hypothesize that a lower DEX dose would provide patients with adequate anesthesia. We will determine the population average dose of DEX (ED50) that provides 50 minutes of tolerance to the tourniquet during a Lidocaine IVRA by a sequential Dixon up-down allocation study. Eligible patients will be enrolled after obtaining informed consent. Patients will receive a standardized IVRA with Lidocaine and DEX adjuvant following a sequential allocation scheme. The first patient will receive a dose of 0.5 µg/kg of DEX. The dose will be then adjusted in 0.1 µg/kg increments for the following patients dependent on the success of the previous patients block. If a patient experiences tourniquet pain prior to 50 minutes after inflation of the distal tourniquet the next patient will receive a higher dose, if he does not experience pain prior to 50 minutes after inflation of the distal tourniquet the dose for the following patient will be decreased. Recruitment will continue until 6 independent crossovers are observed with a minimum of 20 patients. The mean and the standard deviation of the ED50 of DEX will be calculated using the modified up-down method. This study will help determine the ED50 of DEX used as an adjuvant in IVRA. Based on the potency ratios of Clonidine vs. DEX, the investigators hypothesize that the dose of DEX needed to achieve 50 minutes of pain free tourniquet time will be closer to 0.125 µg/kg rather than 0.5 µg/kg, a 75% reduction in the dose studied.

NCT ID: NCT05280223 Completed - Clinical trials for Carpal Tunnel Syndrome

Dexmedetomidine Versus Hyalase Treatment of Carpal Tunnel Syndrome

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Carpal tunnel syndrome (CTS) is a common peripheral entrapment neuropathy, this study aims to investigate if, and to what extent hydro-dissection hyalase and saline versus dexmedetomidine upon the median nerve could offer symptoms and clinical improvement

NCT ID: NCT05261880 Completed - Clinical trials for Carpal Tunnel Syndrome

Comparative Effect of Scaphoid, Hamate Mobilization and Neural Mobilization in Patients With Carpal Tunnel Syndrome

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

To rule out the effects bone mobilization and neural mobilization in Carpal Tunnel Syndrome.

NCT ID: NCT05253729 Completed - Clinical trials for Carpal Tunnel Syndrome

Efficacy of Focused Shockwave Therapy in Patients With CTS

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

Carpal tunnel syndrome (CTS) is the most common entrapment of upper extremity. Patients with CTS will experience symptoms of pain, numbness of tingling sensation along the median nerve distribution. In more severe case, patients may have difficult manipulating objects that disturb function and patient's quality of life. Extracorporeal Shockwave Therapy (ESWT) is one of physical modalities that uses to treat many musculoskeletal disorders. For CTS, previous evidence showed that ESWT can improve symptoms, function as well as electrophysiologic parameters. However, standardized guidelines as well as the study in patients with moderate to severe CTS has not been established. Thus, the objective of the present study was to evaluate efficacy of ESWT in term of symptoms, function, electrophysiologic parameters, as well as sonography of median nerve in patients with moderate to severe CTS.

NCT ID: NCT05222126 Completed - Clinical trials for Carpal Tunnel Syndrome

Efficacy of Ultrasound-Guided Hydrodissection in Carpal Tunnel Syndrome

Start date: September 20, 2022
Phase: N/A
Study type: Interventional

The aim of our study is to determine the effectiveness of US-guided hydrodissection of the median nerve in different contents and volumes in patients diagnosed with mild to moderate carpal tunnel syndrome.

NCT ID: NCT05213819 Completed - Clinical trials for Carpal Tunnel Syndrome

Phonophoresis, Low-Level Laser Therapy and Exercise in the Treatment of Carpal Tunnel Syndrome

Start date: February 20, 2013
Phase: N/A
Study type: Interventional

Carpal tunnel syndrome (CTS) is the most common peripheral nerve compression syndrome. There is insufficient evidence about the efficacy and superiority of conservative treatment methods. The purpose of this study was to evaluate the additional contribution of phonophoresis and Low-Level Laser Therapy (LLLT) to exercise in patients with the CTS. Study design: A single-blind randomized controlled study. Methods: Forty-five patients with clinical and electrophysiologic evidence of moderate CTS were included in the study. The patients were randomized into three groups. Group 1 received phonophoresis and exercise, group 2 received LLLT and exercise and group 3 received exercise alone. All patients were evaluated electrophysiologically, clinically and ultrasonographically before treatment and 6th and 12th week after the treatment.

NCT ID: NCT05207566 Completed - Clinical trials for Carpal Tunnel Syndrome

Reliability And Validity Of Urdu Version Of Boston Carpal Tunnel Syndrome Questionnaire

Start date: May 30, 2021
Phase:
Study type: Observational

Translate and culturally adapt Boston Carpal Tunnel Syndrome Questionnaire into Urdu language and find its reliability and validity in Pakistani Carpal Tunnel Syndrome patients To check its correlation with Disabilities of the Arm, Shoulder and Hand questionnaire and Visual Analog Scale.