Risk Assessment of Carotid Plaques Using 3D Contrast-Enhanced Ultrasound

Status Active, not recruiting

Clinical Trial Summary

This is an open-label, non-randomized study conducted at Thomas Jefferson University comparing pressure-gradient estimates (obtained between a carotid plaque and the carotid artery) to imaging and histology markers of plaque vulnerability. There is an inverse relationship between the subharmonic signal magnitude from contrast-enhanced ultrasound microbubbles and ambient pressure. This pressure estimation technique (referred as SHAPE) will be used to estimate the pressure gradient across the carotid plaque cap noninvasively in vivo.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04643431
Study type	Interventional
Source	Thomas Jefferson University
Contact
Status	Active, not recruiting
Phase	Phase 4
Start date	December 1, 2020
Completion date	May 1, 2024

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