Carotid Atherosclerosis Clinical Trial
Official title:
A Mechanistic, Non-randomised Study to Examine the Uptake of a Specific Radionuclide (61CuATSM) in Carotid Artery Plaque
The build up of plaque in the wall of the artery supplying blood to the brain poses a risk of stroke when the plaques become unstable and fragile. It is important to determine which patients are most at risk so that surgery can be performed. There is evidence that the risk is greatest when these plaques become oxygen deficient (hypoxic). The investigators wish to use PET imaging to identify hypoxic plaque, to help decide whether and when to perform surgery. The investigators have developed radiotracers (imaging agents) for this purpose, and this study is to determine whether they will work in patients.
n/a
Observational Model: Case-Only, Time Perspective: Prospective
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03248401 -
Effect of Cilostazol on Carotid Atherosclerosis Estimated by 3D Ultrasound in Patients With Type 2 Diabetes
|
Phase 4 | |
Withdrawn |
NCT03630835 -
99m Tc-ANNexin-V-128 Scintigraphy for the Identification of Complicated Carotid Atherosclerotic Plaques
|
Phase 2/Phase 3 | |
Completed |
NCT02722720 -
Carotid Arteries Stenting Complications: Transradial Approach Versus Transfemoral
|
N/A | |
Completed |
NCT01893489 -
Visualization of Carotid Atherosclerosis by 68Ga-MSA
|
Phase 1 | |
Withdrawn |
NCT00861159 -
RLIP76 in Human Serum in Adults With Rheumatologic Diseases
|
N/A | |
Recruiting |
NCT01743404 -
Study of Anti-atherosclerotic Activity of Inflaminat in Asymptomatic Participants With Subclinical Atherosclerosis
|
Phase 2 | |
Completed |
NCT00636766 -
Diagnosis and Therapy of Vulnerable Atherosclerotic Plaque
|
N/A | |
Recruiting |
NCT06166121 -
Study on Hyperlipidemia Combined With Carotid Atherosclerosis With ShenJu Granules
|
N/A | |
Withdrawn |
NCT03382249 -
Sonodynamic Therapy Manipulates Atherosclerosis Regression Trial on Patients With Carotid Atherosclerotic Plaques
|
Phase 1/Phase 2 | |
Recruiting |
NCT04679727 -
The Carotid Artery Multi-modality Imaging Prognostic (CAMP) Study
|
||
Withdrawn |
NCT02995642 -
Targeted PET/CT and PET/MRI Imaging of Vascular Inflammation
|
Phase 2 | |
Completed |
NCT00001368 -
Potential Risk Factors for Stroke
|
Phase 1 | |
Recruiting |
NCT04537403 -
PET Detection of CCR2 in Human Atherosclerosis
|
Phase 1 | |
Recruiting |
NCT05800821 -
Prediction of Cerebral Hyperperfusion Syndrome After Carotid Revascularization Using Deep Learning
|
||
Completed |
NCT00147797 -
Influence of Pravastatin on Carotid Artery Structure and Function in HIV-infected Patients Under Antiretroviral Therapy
|
N/A | |
Completed |
NCT00147251 -
Stop Atherosclerosis in Native Diabetics Study
|
Phase 4 | |
Completed |
NCT00180518 -
ACCULINK for Revascularization of Carotids in High Risk Patients "The ARCHeR Trial"
|
Phase 2/Phase 3 | |
Completed |
NCT05230576 -
Intelligent Detection of Carotid Plaque and Its Stability Based on Deep Learning Dynamic Ultrasound Scanning
|
||
Terminated |
NCT03764306 -
New Ischemic Cerebral Lesions After Endarterectomy vs. Stenting for the Treatment of Symptomatic Carotid Stenosis
|
N/A | |
Recruiting |
NCT05838547 -
CANF-Comb-II PET-MR in Atherosclerosis Multisite
|