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Carotid Artery Stenosis clinical trials

View clinical trials related to Carotid Artery Stenosis.

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NCT ID: NCT02966418 Completed - Clinical trials for Carotid Artery Stenosis

Hypoxic Preconditioning on Patients

Start date: January 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to study the effects of intermittent whole-body hypoxic preconditioning on patients with carotid artery stenosis.

NCT ID: NCT02850081 Completed - Clinical trials for Carotid Artery Stenosis

Statin Neuroprotection and Carotid Endarterectomy: Safety, Feasibility and Outcomes

STANCE
Start date: June 1, 2017
Phase: Phase 3
Study type: Interventional

The investigators hypothesize that pre-operative statin use is neuroprotective at maximal doses. The goals are to determine the safety, feasibility, and efficacy of maximizing statin doses for two weeks (12-18 days) prior to CEA using change in performance on a battery neuropsychometric tests as outcome measure. Study will recruit patients based on their preexisting statin regimen. The investigators hypothesize that in asymptomatic CEA patients: 1) Pre-operative statin use is neuroprotective against early cognitive dysfunction (eCD) and lowers the risk of early mortality. 2) Maximal doses may be essential in achieving optimal neuroprotection against eCD.

NCT ID: NCT02802072 Completed - Clinical trials for Carotid Artery Stenosis

Enterprise Stent Implantation in the Treatment of Carotid Artery Stenosis With Ischemic Stroke

Start date: January 2013
Phase: N/A
Study type: Interventional

To investigate the long-term effects of intracranial implantation of Enterprise stent system versus antiplatelet medication on neurologic deficits, daily living abilities, and carotid artery stenosis in patients with atherosclerotic ischemic stroke.

NCT ID: NCT02800174 Completed - Clinical trials for Carotid Artery Stenosis

Smart Nitinol Stent System for the Treatment of Severe Atherosclerotic Carotid Stenosis

Start date: June 2006
Phase: N/A
Study type: Interventional

To validate the long-term effects of implantation of the self-expanding Smart nitinol stent system for the treatment of severe atherosclerotic carotid stenosis in a 2-year follow-up study of a large patient cohort

NCT ID: NCT02689414 Completed - Clinical trials for Peripheral Artery Disease

A Study of Remote Ischaemic Preconditioning in Patients With Atherosclerosis Undergoing Vascular Surgery

Start date: January 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effect of preoperative remote ischaemic preconditioning (RIPC) on organ damage and the functional characteristics of arteries in patients undergoing vascular surgery. In addition, we investigate the connection between RIPC and changes in the functional characteristics of arteries and low molecular weight metabolites.

NCT ID: NCT02677545 Completed - Clinical trials for Carotid Artery Stenosis

Ticagrelor Versus Clopidogrel in Carotid Artery Stenting

PRECISE-MRI
Start date: December 2016
Phase: Phase 2
Study type: Interventional

Patients with symptomatic or asymptomatic carotid stenosis in whom carotid artery stenting is planned are randomised between antiplatelet therapy with ticagrelor plus aspirin or clopidogrel plus aspirin and examined with brain MRI before and after stent treatment. The proportion of patients with new ischaemic lesions on MRI after treatment is compared between the two groups.

NCT ID: NCT02657707 Active, not recruiting - Clinical trials for Carotid Artery Stenosis

Evaluation of the Roadsaver Stent Used in Conjunction With the Nanoparasol Embolic Protection System for Carotid Artery Stenosis

Start date: April 21, 2016
Phase: N/A
Study type: Interventional

A prospective, multicenter, single-arm, open label clinical study to evaluate the safety and effectiveness of MicroVention, Inc. Roadsaverâ„¢ Carotid Stent System used in conjunction with the Nanoparasol® embolic protection system for the treatment of carotid artery stenosis in patients with elevated risk for adverse events following carotid endarterectomy.

NCT ID: NCT02629653 Completed - Stroke Clinical Trials

Body Cooling During Carotid Endarterectomy: No-profit, Open, Mono-centric, Feasibility Study

Start date: December 2013
Phase: N/A
Study type: Interventional

Aim of the study is to determine whether endovascular systemic cooling to a target temperature of 34-35°C initiated before, and maintained during Carotid EndoArterectomy (CEA), is feasible and safe

NCT ID: NCT02476396 Recruiting - Stroke Clinical Trials

Structural Stability of Carotid Plaque and Symptomatology

Start date: November 9, 2015
Phase:
Study type: Observational

The purpose of the research is to understand structural plaque abnormalities that make a carotid plaque unstable and brake off (embolize) which would help to predict and treat individuals who are likely to suffer not only classic episodic major strokes but also cognitive impairment.

NCT ID: NCT02450734 Completed - Clinical trials for Carotid Artery Stenosis

Ultrasound-guided Intermediate Cervical Plexus Block for Carotid Surgery

Start date: April 2011
Phase: N/A
Study type: Observational

Since stroke and myocardial ischemia are major causes of perioperative morbidity and mortality associated with carotid endarterectomy, monitoring the brain and ensuring the best hemodynamic stability are important goals of perioperative management. The investigators conducted a prospective observational study about efficacy and safety of the ultrasound-guided intermediate cervical plexus block (CPB), with early (immediate postoperative) and mid-term (day 30) outcomes in awake patients undergoing carotid endarterectomy.