99mTc-rhAnnexin V-128 Imaging for Carotid Atherosclerosis

Status Terminated

Clinical Trial Summary

This was a single-center, single-dose, study comprising a Proof of Concept (PoC) part and a subsequent Phase II part. The study was being done to assess the ability of the radiotracer 99mTc-rhAnnexin V-128 to image atherosclerotic plaque that might rupture and break off artery walls. This is caused by apoptosis or cell death in the plaque. These ruptured plaques can block blood circulation in the arteries causing a lack of oxygen to the tissues. Atherosclerotic plaques can build up on any artery in the body.

Clinical Trial Description

The sponsor decided to terminate the study earlier than planned due to strategic decisions to focus the AAA development portfolio on oncology theragnostics and not based on safety concerns. Novartis acquired Advanced Accelerator Applications SA. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02667457
Study type	Interventional
Source	Advanced Accelerator Applications
Contact
Status	Terminated
Phase	Phase 2
Start date	June 23, 2016
Completion date	November 19, 2018

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