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NCT05109299 Clinical Trial

Antibacterial Effect of Miswak Toothpaste Compared to Fluoride Toothpaste

Caries Clinical Trial

Official title:
Antibacterial Effect of Miswak Toothpaste Compared to Fluoride Toothpaste in High Caries Risk Patients: Randomized Clinical Trial

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT05109299
Other study ID # miswak
Secondary ID
Status Not yet recruiting
Phase N/A
First received
Last updated
Start date December 1, 2021
Est. completion date April 30, 2022

Study information
Verified date October 2021
Source Cairo University
Contact Omar O Shaalan, PhD
Phone 00201122665661
Email omar.shaalan@dentistry.cu.edu.eg
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Meswak is scientifically formulated herbal toothpaste with pure extract of the Miswak plant 'Salvadore Persica', the famous 'Toothbrush Tree' used for centuries. The astringent and anti-bacterial properties of Meswak helps reduce tooth decay , fight plaque and prevent gum diseases. Miswak Herb is a rare, potent, priceless, wonder herb that delivers incredible Dental Care benefits.

Description:

This study is a randomized clinical trial, with parallel study design, 1:1 allocation ratio and superiority framework. The aim of the current trial is to evaluate antibacterial effect miswak toothpaste compared to fluoride toothpaste in high caries risk patients.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 32
Est. completion date April 30, 2022
Est. primary completion date March 30, 2022
Accepts healthy volunteers No
Gender All
Age group 18 Years to 25 Years
Eligibility Inclusion Criteria: - High caries risk patients. - At least one carious tooth according to CAT caries risk assessment model. - Patient compliance Exclusion Criteria: - Participant in another trial. - Using another antimicrobial agents since one month of sampling. - Systemic diseases or concomitant medication affecting salivary flow. - Parafunctional habits. - Pregnancy.

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• Miswak toothpaste
Dabur Meswak is scientifically formulated herbal toothpaste with pure extract of the Miswak plant 'Salvadore Persica'
• Fluoride toothpaste
1450 ppm fluoride toothpaste

Locations
Country Name City State
Egypt Faculty of Dentistry, Cairo University Cairo El Manial

Sponsors (1)
Lead Sponsor Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary streptococcus mutans count Counting streptococcus mutans, Measurement: Mitis-Salivarius agar plate, Unit: CFUs/mL 3 months
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