Clinical Trials Logo
  1. Home
  2. Caries
  3. NCT01700712

Acid Production in Dental Plaque After Exposure to Probiotic Bacteria

Caries Clinical Trial

Clinical Trial Summary

The increasing interest in probiotic lactobacilli in health maintenance has raised the question of potential risks. One possible side effect could be an increased acidogenicity in dental plaque. The aim of this study was to investigate the effect of probiotic lactobacilli on plaque lactic acid (LA) production in vitro and in vivo.

Methods. subjects (n=18) were given lozenges with probiotic lactobacilli (L. reuteri DSM 17938 and ATCC PTA 5289) or placebo for two weeks in a double-blinded, randomized cross-over trial. The concentration of LA in supragingival plaque samples was determined at baseline and after 2 weeks. Salivary counts of mutans streptococci (MS) and lactobacilli were estimated with chair-side methods.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01700712
Study type Interventional
Source University of Copenhagen
Contact
Status Completed
Phase N/A
Start date December 2010
Completion date October 2011
View Details
See also
  Status Clinical Trial Phase
Active, not recruiting NCT05311657 - Oral Health and Severe COPD
Not yet recruiting NCT06438926 - Prevalence of Dental Caries in Patients With Dental Crowding
Completed NCT01529606 - Cold Plasma for Dental Restoration and Caries Prevention N/A
Completed NCT06072742 - Effect of Lifestyle on Caries and Apical Periodontitis
Completed NCT04679558 - Antibacterial Effect of Chlorhexidine Added to the Preventive Protocol in Adolescent Special Needs Early Phase 1
Active, not recruiting NCT04933123 - Clinical Evaluation of a Dental Glass Ceramic in the Indirect Restorative Therapy N/A
Withdrawn NCT02202304 - The Effects of Chlorhexidine/Thymol Varnish on Partial Denture Patient Phase 4
Not yet recruiting NCT04889196 - The Efficiency and Gingival Health Status of Hall Versus SDF Techniques in the Management of Carious Primary Molars Phase 3
Active, not recruiting NCT04708223 - Prospective, Split-mouth, Comparative Study to Compare Clinical Outcomes of Two Different Posterior Composite N/A
Completed NCT06140745 - Evaluation of Dentifrice Formulations to Remineralize Enamel and Dentine Subsurface Lesions in a Double-Blind In-Situ Clinical Trial N/A
Recruiting NCT05144711 - Management of Deep Carious Lesions in Adults N/A
Not yet recruiting NCT03656432 - Effect of CPP-ACP With/Without Fl on White Spot Lesion,Salivary pH and fl Release in High Caries Risk Patients Phase 3
Not yet recruiting NCT02933463 - Clinical Effectiveness of Embrace Wetbond and Clinpro as Pits and Fissure Sealants in Young Permanent Molars N/A
Completed NCT02998814 - Clinical Follow Up of a Fissure Sealant Placed With Different Adhesive Protocols: 2-Year Randomized Split Mouth Study N/A
Completed NCT02027597 - Improving Oral Health With Serious Games N/A
Not yet recruiting NCT05064566 - Evaluation of Caries Detection Methods
Completed NCT06010732 - In Situ Comparison of the Remineralization Potential of Optimized Fluoride Dentifrice With Control Fluoride Dentifrice Phase 3
Recruiting NCT05211843 - Saliva Insulin as Biomarker of Risk Factors for Metabolic Dysregulation and Caries N/A
Not yet recruiting NCT05070416 - Lithium Disilicate Crowns Study N/A
Completed NCT02418520 - The Effect of Miswak Chewing Sticks on the Oral Helicobacter Pylori Infection N/A