Caries Prevention Clinical Trial
Official title:
Comparing the Bond Strength,Microleakage and the Clinical Performance of Three Different Pit and Fissure Sealants (An in Vitro,in Vivo Study)
The aim of the study is :-
1. To evaluate and compare the microleakage of three different fissure sealants(resin-based
Clinpro sealant, Moisture tolerant resin-based Embrace WetBond sealant and glass ionomer
Fuji Triage sealant) in vitro.
2. To evaluate and compare the bond strength of three different fissure
sealants(resin-based Clinpro sealant, Moisture tolerant resin-based Embrace WetBond
sealant and glass ionomer Fuji Triage sealant) in vitro.
3. To clinically evaluate and compare the retention of three different fissure
sealants(resin-based Clinpro sealant, Moisture tolerant resin-based Embrace WetBond
sealant and glass ionomer-based Fuji Triage sealant).
4. To clinically evaluate and compare the caries prevention effect of three different
fissure sealants(resin-based Clinpro sealant, Moisture tolerant resin-based Embrace
WetBond sealant and glass ionomer-based Fuji Triage sealant).
Total of 60 first permanent molar in male and female children aged between 6-9 years included
in this prospective study will be selected randomly from the outpatient Pediatric Dentistry
and Dental Public Health Department Faculty of Dentistry Ain Shams University.
Informed consent will be signed for each case by the patient's parent or guardian after
thorough explanation of the study.
Procedural Steps:
In vivo
1. Teeth will be divided equally into 3 groups randomly according to the type of sealant
used.
2. Pit and fissure sealant application will be conducted by a single operator.
3. A thorough oral prophylaxis of both upper and lower arches was done, followed by
polishing using a slurry of pumice and rotating brush to ensure removal of debris from
fissures.
4. The occlusal surfaces were then thoroughly cleaned with water to remove all traces of
pumice. Isolation of permanent first molars will be obtained using cotton rolls and a
saliva ejector.
Group 1(Clinpro sealant)Active control
1. The occlusal surface will be dried and etched with 37% phosphoric acid gel for 30 s
2. Thorough rinsing for 30 s using an oil-free air-water syringe.
3. Clinproâ„¢ Sealant then applied with the brush applicator and light cured for 20 s using
visible light cure unit.
Group 2(Embrace WetBond sealant)
1. Etching the teeth for 15 seconds with a phosphoric-acid etchant.
2. Then rinse the etchant from the teeth with an air-water spray for 10 seconds,
3. followed by very light drying of the treated surfaces. With Embrace Wet-Bond, the
typical dull, frosted appearance of the etched surface is not desired. Rather, the
surface should be lightly dried and very slightly moist with a glossy appearance. To
accomplish this, a cotton pellet should be used to remove the excess moisture There
should be no visible pooling or drops of water on the tooth surfaces.
4. Applying the Embrace WetBond sealant to the occlusal surface using the supplied
applicator tip After dispensing, use a brush applicator to place the sealant, covering
all pits and fissures and extending onto the cusp ridges. The final sealant thickness
upon application should be at least 0.3 mm.
5. After application, light-cure the sealant for 10 seconds, holding the light-curing probe
at right angles to the occlusal surface as close as possible using a high-intensity
curing light.
Group 3 (Fuji Triage sealant)
1. The occlusal surfaces conditioned with Dentin Conditioner for 20 s and then rinsed for
another 20 s, followed by drying by blotting with a cotton pellet and gently blowing
with an air syringe. The surfaces appeared moist and not desiccated.
2. Fuji Triage sealant will then applied to the occlusal surface using a plastic-filling
instrument and a disposable nylon brush to spread it into the pits and fissures.
3. The material is self-curing, but a light-curing device can be used for 20 to 40 seconds
to hasten setting.
4. When the material loses its glossy appearance, one drop of Fuji Coat is dispensed The
coating is applied with a brush to the treated surface and adjacent areas, and light
curing is applied .
Articulating paper was used to check the occlusion and any premature contacts were adjusted.
The patients were instructed not to eat or drink anything for 30 min, and not to bite or chew
on hard substances for the rest of the day. The patients were recalled after a time interval
of 1 and 6 months to evaluate the retention and development of caries using Modified
Simonsen's criteria.
Criteria for evaluation: (Modified simonsen's criteria) Score 0: No loss of sealant and no
evidence of caries Score 1: Partial loss of sealant and no evidence of caries Score 2:
Partial loss of sealant and evidence of caries. Score 3: Complete loss of sealant and no
evidence of caries Score 4: Complete loss of sealant and evidence of caries. On recall at 3
and 6th month interval, the sealants were evaluated by visual and tactile examination with a
sharp probe for retention. The teeth were visually inspected for caries. The data obtained
were tabulated and subjected to statistical analysis.
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