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Nano-hydroxyapatite and Ozone - Effect on Approximal Initial Caries

Caries,Dental Clinical Trial

Official title:
Influence of Nano-hydroxyapatite and Ozone on Approximal Initial Caries

Clinical Trial Summary

Objectives: to assess the efficiency of three methods of enamel remineralization on initial approximal caries: 1. a nano-hydroxyapatite gel, 2. gaseous ozone therapy 3. combination of a nano-hydroxyapatite gel and ozone.

Materials and Methods: Patients (n=92, age 20-30y) with initial approximal enamel lesions on premolar and molar teeth (n=546) randomly allocated to three groups subjected to a 6-months treatment: Group I: domestic nano-hydroxyapatite remineralizing gel, group II: in-office ozone therapy, group III: both remineralizing gel and ozone therapy. Caries lesions assessed on bitewing radiographs at baseline, after 1 year and after 2 years.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04147091
Study type Interventional
Source Pomeranian Medical University Szczecin
Contact
Status Completed
Phase Phase 2/Phase 3
Start date February 2012
Completion date December 2016
View Details
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