Apical Periodontitis Clinical Trial
Official title:
Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth: A Randomized Clinical Trial
The primary goal of the study is to compare the success rates of pulpal anesthesia (defined as ability to complete the intended dental procedure without the need for rescue anesthesia) between Kovanaze nasal mist and Articaine needle anesthesia.
In June 2016, an intranasal delivery system of local anesthesia called Kovanaze, gained FDA
approval. Kovanaze is available as a 0.2 ml metered spray and is intended to achieve pulpal
anesthesia of 5 maxillary teeth on either side of the face.
With the ability to avoid the traditional painful injection Kovanaze offers promise in the
field of maxillary anesthesia and this study intends to:
1. Compare Kovanaze to conventional needle anesthetic in adults
2. Evaluate patient anxiety, tolerance and acceptability of Kovanaze in patients undergoing
dental procedures
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT04552132 -
Postoperative Pain and Healing in Teeth Treated With GentleWave or EndoActivator
|
N/A | |
| Completed |
NCT04514991 -
Bone Regenerative Techniques in Endodontic Microsurgery
|
N/A | |
| Completed |
NCT01904552 -
Accuracy of ERCLMDs in Teeth With Apical Periodontitis
|
Phase 1 | |
| Completed |
NCT05792787 -
Association Between Apical Periodontitis and Atherosclerotic Cardiovascular Diseases
|
||
| Completed |
NCT06072742 -
Effect of Lifestyle on Caries and Apical Periodontitis
|
||
| Completed |
NCT06226740 -
Effectiveness of Different Obturation Techniques
|
N/A | |
| Completed |
NCT04126928 -
Validation of PUFA Index in Assessing Untreated Dental Caries Among Malaysian Adult Subpopulation
|
N/A | |
| Recruiting |
NCT05439330 -
Application of a Dental-dedicated MRI in the Diagnosis of Temporomandibular Joint Disorders, Tissue Alterations Related to Third Molars, Periapical and Periodontal Inflammatory Diseases, and Implant Treatment Planning
|
N/A | |
| Recruiting |
NCT06005545 -
A Study to Compare Various Root Canal Cleaning Devices Based on Cavitation,Ultrasonic and Conventional Methods.
|
N/A | |
| Completed |
NCT02681276 -
Clinical and Microbiological Evaluation of 0.5% Versus 3% Sodium Hypochlorite in Root Canal Treatment
|
N/A | |
| Completed |
NCT04072926 -
Effects of PDT and Bioceramic Filling on Periapical Healing and Postoperative Pain After Endodontic Retreatment
|
Early Phase 1 | |
| Completed |
NCT03711942 -
Comparison of Healing of Apical Periodontitis in Periodontally Diseased and Healthy Patients.
|
N/A | |
| Completed |
NCT03409887 -
Effect of Intraorifice Barrier on Healing of Apical Periodontitis
|
N/A | |
| Completed |
NCT03171376 -
Effect of Coronal Extent of Obturation on Endo-perio Lesions
|
N/A | |
| Recruiting |
NCT06043453 -
Revitalization of Traumatized Immature Permanent Teeth
|
||
| Completed |
NCT03987659 -
Therapeutic Irrigation Procedures to Treat Apical Periodontitis
|
N/A | |
| Completed |
NCT03288467 -
Effect of Sodium Hypochlorite Concentration on Success of Non-surgical Root Canal Treatment
|
N/A | |
| Recruiting |
NCT03527602 -
FE in Anterior Teeth
|
N/A | |
| Completed |
NCT04545307 -
Transplantation of Allogeneic MSC in Patients With Pulp Necrosis and Chronic Apical Periodontitis
|
Phase 2/Phase 3 | |
| Recruiting |
NCT03243357 -
In Vivo Assessment of Endodontics Procedures
|
N/A |