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Caries, Dental clinical trials

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NCT ID: NCT05919576 Completed - Caries,Dental Clinical Trials

Near Infrared Technology for the Detection of Proximal Caries

Start date: August 8, 2022
Phase:
Study type: Observational

This study aims to determine the effectiveness of an intraoral scanner with near-infrared imaging (NIRI) for the diagnosis of proximal caries.

NCT ID: NCT05810389 Completed - Caries,Dental Clinical Trials

EVALUATION OF AN ALTERNATIVE TECHNIQUE FOR THE APPLICATION OF SODIUM FLUOROPHOSPHATE: A 2-YEARS DOUBLE-BLIND RCT

Start date: April 1, 2017
Phase: Phase 4
Study type: Interventional

he study was designed as a double-blind three-parallel-group randomized controlled trial, in which the evaluators and a researcher, not involved in the evaluation process, was responsible for the randomization process, were masked to the group assignment. The study will be carried out at 2 schools of the Metropolitan Area of Buenos Aires where school programs are developed by the Department of Preventive and Community Dentistry of the University of Buenos Aires, and that present homogeneous characteristics in terms of social risk. The children (n=244) attending those primary schools will be the population object of the trial. Clinical examinations Each child will go under a clinical examination to determine dental status according to the ICDAS II criteria (Pitts, 2005) and the Caries Treatment Need Index (CTNI). Intervention Children will be divided into three different groups according to the mode of treatment: - NaF varnish group (NaFV) Professional application of 5% NaF varnish twice a year pH 7 (ClinPro White Varnish®) according to manufacturer's instructions. - APF in tray Group (APFt) Professional application of APF 1.23% twice a year pH 3.5 (Klepp®) with tray according to manufacturer's instructions - APF in toothbrush group (APFtbru) Professional application of APF 1.23% twice a year pH 3.5 (Klepp®) with toothbrush 2 minutes brushing according to manufacturer's instructions. Dental examination and Monitoring Observations and clinical examinations will be conducted at schools. After 12 and 24 months, the clinical examination will be repeated to assess the dental status of schoolchildren following the same criteria described. The presence of new caries lesions will be taken as a dependent variable. So sound surfaces on baseline will be observed for 24 months.

NCT ID: NCT05792800 Not yet recruiting - Caries,Dental Clinical Trials

Dental Practitioners KAP Regarding Caries Preventive Measures in Cairo and Riyadah

Start date: September 2023
Phase:
Study type: Observational

The study aims to evaluate the knowledge, attitude, and practice of dental practitioners from Cairo and Riyadh regarding caries preventive measures.

NCT ID: NCT05792215 Not yet recruiting - Caries,Dental Clinical Trials

KAP of Dental Practitioners Regarding CRA

Start date: September 2023
Phase:
Study type: Observational

The aim of the study is to evaluate the knowledge, attitude, and practice of a group of dental practitioners from Cairo and Riyadh regarding caries risk assessment and management.

NCT ID: NCT05756413 Recruiting - Caries,Dental Clinical Trials

Birth to Three - Cavity Free

BTCF
Start date: March 1, 2023
Phase: N/A
Study type: Interventional

Early childhood caries (ECC) is a potentially painful and debilitating disease, which represents a significant public health problem among young children. There are profound disparities in ECC experiences such that children from minority and low-income families suffer a disproportionate share of the disease burden. The likelihood of parents of high-ECC risk young children seeking prevention in dental facilities is low; therefore, there is a need to increase preventive dental opportunities where these children already seek health care services. In particular, there is an urgent need to develop and evaluate ECC behavioral interventions for use in public health settings attended by high-risk children. Many authors recommend early implementation of oral health education as one means of preventing ECC. However, major issues discussed in the oral health promotion literature involve a lack of effectiveness among programs based on education alone, as well as a lack of high quality preventive interventions using evidence-based psychological and behavioral strategies. Our research team has been the first to introduce to the ECC prevention arena the self-determination theory (SDT) of motivation, internalization, and healthy functioning, proven effective in promoting positive behavioral changes in several other fields, including oral health care. The investigators have demonstrated that SDT has great promise as a motivational approach by providing evidence, based on results from our R21 (R21-DE016483) study, of the effectiveness of SDT in changing several desirable oral health behaviors for ECC prevention. Building upon the rigor of our previous experience and formative research work in the past several years, the investigators propose a Stage II NIH Model research project that will compare the efficacy of autonomy-supportive videotaped oral health messages framed by SDT to more traditional neutral videotaped messages. The investigators intend to recruit 634 pregnant mothers enrolled in Iowa Women, Infants and Children (WIC) Supplemental Nutrition Programs and follow them until their future child is 36 months old. The primary outcome of interest will be children's caries status. Secondary outcomes will be changes in children's oral health behaviors conducive to better oral hygiene and dietary habits, as well as lower levels of dental plaque and mutans streptococci.

NCT ID: NCT05600517 Recruiting - Caries,Dental Clinical Trials

Evaluation of Caries Prevention Based on Genetic Etiology and Risk.

PRECARIES
Start date: August 25, 2021
Phase: N/A
Study type: Interventional

Dental caries affects billions of people worldwide and involves saliva immunodeficiency, commensal pathogen and exposure (lifestyle) causal subtypes of the disease. Up to 85% of adolescents in Swedish and other low prevalence populations are caries-free while the remaining 15% show high, recurrent caries activity. Accordingly, there is a lack of cost-effective risk assessment and prevention tools for personalized oral care. This randomized adaptive clinical trial (RCT) evaluates both caries prevention based on genetic etiology and risk, as a consequence of saliva immunodeficiency genes specifying individuals as susceptible or resistant to caries, and the effect of intensified versus selfcare traditional prevention on the two groups.

NCT ID: NCT05546528 Recruiting - Caries,Dental Clinical Trials

Photobiomodulation on Major Salivary Glands in Children With Caries Activity

Start date: January 20, 2023
Phase: N/A
Study type: Interventional

The purpose of this trial is to evaluate the efficacy of photobiomodulation of the major salivary glands on salivary parameters in children with caries activity.

NCT ID: NCT05362461 Recruiting - Caries,Dental Clinical Trials

Diagnostic Ability of Near Infrared Transillumination Detecting Interproximal Caries as Compared to Conventional Bitewing Radiographs

Start date: October 31, 2022
Phase:
Study type: Observational

Specific Aims 1. To determine the diagnostic efficacy of CariVu and BWX for detecting interproximal carious lesions in primary dentition BWX and CariVu images will be taken in random order. Number and depth of interproximal carious lesions will be determined by two independent examiners using both CariVu images and BWX. Intra- and inter-rater agreement and disagreement will be determined for all the images and radiographs. 2. To determine acceptability and comfort of CariVu and BWX as perceived by patient, parent and independent observer BWX and CariVu images will be taken in a random order and patient and parent will be given a questionnaire to complete as exit survey. The questionnaire will include few questions to determine perceived acceptability and comfort by parent and patient for either methods (CariVu and BWX). An independent observer (dental assistant) who is masked for the hypothesis of the study will be given a similar questionnaire to evaluate patient behavior using standard behavior assessment scales. 3. To determine difference in chair-side time required for BWX and CariVu image generation Time required to generate both, BWX and CariVu images will be documented by an independent observer (dental assistant) who is masked for the hypothesis of the study and will be compared to determine the overall clinical chair-side time required for generating diagnostic images for efficient and accurate treatment planning

NCT ID: NCT05306691 Not yet recruiting - White Spot Lesion Clinical Trials

Remineralizing Efficacy of Giomer Varnish vs. Fluoride Varnish in Management of White Spot Lesions in Adult Patients

Start date: May 15, 2022
Phase: Early Phase 1
Study type: Interventional

To evaluate the remineralizing capability of biosmart S-PRG barrier coat varnish and its employment in clinical practice

NCT ID: NCT05276154 Not yet recruiting - Caries,Dental Clinical Trials

Clinical Performance of Thermoviscous Bulk Fill Resin Composites in Comparison to Conventional Packable Bulk Fills

Start date: April 15, 2022
Phase: N/A
Study type: Interventional

This clinical trial will be conducted to compare the clinical performance of the thermo-viscous preheated bulk fill composite in the management of carious lesions in posterior teeth in adult patients over 12 months.