Acute Health Effects of High Temperature Exposure

Status Active, not recruiting

Clinical Trial Summary

This is a randomized controlled human exposure crossover study. Investigators aims to assess the acute effects of high temperature exposure and the underlying mechanisms.

Clinical Trial Description

The investigators will conduct a randomized controlled human exposure crossover study among about 40 healthy young adults in Shanghai, China. Each subject will be exposed twice: once to the high temperature (32℃) and once to moderate temperature (22℃) in a chamber for about 2 hours. During the exposure session, each subject will be requested to rest. Health examinations will be conducted immediately prior to exposure, during the period of exposure and after exposure. Health examinations include symptom questionnaire, blood pressure tests, cognitive function tests, magnetic resonance imaging, skin tests, spirometry, and Holter monitoring. Investigators plan to collect blood, urine and oropharyngeal swabs samples. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05575752
Study type	Interventional
Source	Fudan University
Contact
Status	Active, not recruiting
Phase	N/A
Start date	October 23, 2022
Completion date	December 31, 2023

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