Stage IV Breast Cancer Clinical Trial
Official title:
Statin Therapy as a Protective Technique for Potential Cardiovascular Event Occurrences Among Breast Cancer Patients Undergoing Chemotherapy Treatment
This randomized pilot clinical trial studies rosuvastatin in treating women with cardiovascular complications who are undergoing chemotherapy for breast cancer. Rosuvastatin may prevent or lessen cardiovascular complications in patients undergoing chemotherapy for breast cancer
OBJECTIVES:
I. Evaluate the feasibility of administering Rosuvastatin to breast cancer patients
undergoing treatment with anthracyclines, paclitaxel, cyclophosphamide, and trastuzumab for
breast cancer.
OUTLINE: Patients are randomized to 1 of 2 treatment arms.
Arm I: Patients receive rosuvastatin orally (PO) once daily for 3 months in the absence of
disease progression or unacceptable toxicity.
Arm II: Patients receive placebo PO once daily for 3 months in the absence of disease
progression or unacceptable toxicity.
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