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Cardiac Transplant Disorder clinical trials

View clinical trials related to Cardiac Transplant Disorder.

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NCT ID: NCT04809051 Completed - Clinical trials for Cardiac Transplant Disorder

Don't Throw Your Heart Away: Patient Study 4

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

This empirical study tests whether transplant center performance data that reflect center donor acceptance rates influence patients and their family members to evaluate centers with high organ decline rates less favorably than centers with low organ decline rates. 400 transplant patients and family members will be recruited from transplant support group social media websites and randomized to one of four different information presentation conditions. Upon viewing a pair of outcome tables corresponding to their condition, the participants are asked to choose which hospital is higher performing (one hospital with a non-selective "accepting" strategy and one hospital with a more selective "cherrypicking" strategy.

NCT ID: NCT04455893 Completed - Clinical trials for Cardiac Transplant Disorder

Don't Throw Your Heart Away: Clinician Study 3

Start date: June 30, 2020
Phase: N/A
Study type: Interventional

Publicly available outcome assessments for transplant programs do not make salient that some programs tend to reject many of the hearts they are offered, whereas other programs accept a broader range of donor offers. The investigators use empirical studies to test whether transplant center performance data (i.e. transplant and waitlist outcome statistics) that reflect center donor acceptance rates influence laypersons to evaluate centers with high organ decline rates less favorably than centers with low organ decline rates. 125 heart transplant clinical personnel will be recruited from International Heart and Lung Society (ISHLT) and the Pediatric Heart Transplant Society (PHTS) and randomized to one of two different information presentation conditions. Participants will be asked to view the table of transplant outcomes corresponding to the condition they were randomized to. Each participant is asked to choose the hospital that they would consider to be "higher-performing" between two hospitals: one hospital with a non-selective, "accepting" strategy (takes all donor heart offers), and one hospital with a more selective, "cherrypicking" strategy (tends to reject donor offers that are less than "excellent" quality).

NCT ID: NCT04176796 Completed - Clinical trials for Cardiac Transplant Disorder

Don't Throw Your Heart Away: Medical Student Study 2

Start date: November 27, 2019
Phase: N/A
Study type: Interventional

Publicly available outcome assessments for transplant programs do not make salient that some programs tend to reject many of the hearts they are offered, whereas other programs accept a broader range of donor offers. The investigators use empirical studies to test whether transplant center performance data (i.e. transplant and waitlist outcome statistics) that reflect center donor acceptance rates influence laypersons to evaluate centers with high organ decline rates less favorably than centers with low organ decline rates. 125 medical student participants will be recruited from University of Pittsburgh Medical School and randomized to one of two different information presentation conditions. Participants will be given an introduction to the donor organ match process, then asked to view the table of transplant outcomes corresponding to the condition they were randomized to. Each participant is asked to choose the hospital that they would consider to be "higher performing" between two hospitals: one hospital with a non-selective, "accepting" strategy (takes all donor heart offers), and one hospital with a more selective, "cherrypicking" strategy (tends to reject donor offers that are less than "excellent" quality).

NCT ID: NCT04133831 Completed - Clinical trials for Cardiac Transplant Disorder

Don't Throw Your Heart Away: Layperson Study 1

Start date: November 15, 2019
Phase: N/A
Study type: Interventional

Publicly available outcome assessments for transplant programs do not make salient that some programs tend to reject many of the hearts they are offered, whereas other programs accept a broader range of donor offers. The investigators use empirical studies to test whether transplant center performance data (i.e. transplant and waitlist outcome statistics) that reflect center donor acceptance rates influence laypersons to evaluate centers with high organ decline rates less favorably than centers with low organ decline rates. 1000 lay participants will be recruited from Amazon Mechanical Turk and randomized to one of five different information presentation conditions. Participants will be given an introduction to the donor organ match process, then asked to view the table of transplant outcomes corresponding to the condition they were randomized to. Each participant is asked to choose between two hospitals: one hospital with an non-selective, "accepting" strategy (takes all donor heart offers), and one hospital with a more selective, "cherrypicking" strategy (tends to reject donor offers that are less than "excellent" quality).

NCT ID: NCT03393793 Completed - Heart Failure Clinical Trials

HEart trAnsplantation Registry of piTie-Salpetriere University Hospital

HEARTS
Start date: January 1, 2009
Phase:
Study type: Observational

Heart transplantation (HTx) is a procedure which is hindered by several complications. The HEARTS registry aims to allow the analysis of risk factors of all post-HTx complications. It consists in an exhaustive data collection at the moment of inclusion, i.e. HTx, knowing that patients underwent a full-fledged evaluation beforehand to evaluate their aptitude to being transplanted. Post-HTx complications include but is not limited to: all-cause mortality, AMR, ACR, CAV, AKI, sepsis, cancer, psychological disorders, metabolic disorders.

NCT ID: NCT03026023 Withdrawn - Hepatitis C Clinical Trials

Preemptive Zepatier Treatment in Donor HCV Positive to Recipient HCV Negative Cardiac Transplant

Start date: August 1, 2018
Phase: Phase 4
Study type: Interventional

This is a proof of concept, single center study for the donation of HCV-positive hearts to HCV negative recipient patients, with preemptive, interventional treatment with 12-16 weeks of grazoprevir and elbasvir (with or without ribavirin) to prevent HCV transmission upon transplantation.

NCT ID: NCT02670408 Recruiting - Clinical trials for Cardiac Transplant Disorder

Diagnostic and Therapeutic Applications of Microarrays in Heart Transplantation

Start date: January 2016
Phase:
Study type: Observational

Demonstrate the impact of the Molecular Microscope Diagnostic System as the standard of care for heart transplant patients.

NCT ID: NCT01760538 Completed - Clinical trials for Cardiac Transplant Disorder

Study on Heart Rate Variability in Cardiac Transplant Recipients With Exercise and After Exercise Training

Start date: August 2001
Phase: N/A
Study type: Interventional

The purpose of the study was to investigate the changes on heart rate variability, exercise capacity, activities of daily living, and quality of life after aerobic exercise training in cardiac transplant recipients.