Cardiac Surgery Clinical Trial
Official title:
Oxygenation Targets in Cardiac Surgery Patients - a Before-and-after Study
Verified date | October 2019 |
Source | Aalborg University Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
During surgery high concentrations of supplementary oxygen are routinely administrated. However, there is increasing evidence of potential harm with liberal oxygen therapy. The hypothesis of the present study is that oxygen therapy adjusted to a normal arterial oxygen target is feasible and will attenuate the side effects of supplementary oxygen therapy. The study design is a before-and-after study in which 25 patients will follow the standard regime with high concentrations of oxygen therapy and 25 patients will be treated with oxygen to achieve a normal value of arterial oxygenation.
Status | Active, not recruiting |
Enrollment | 50 |
Est. completion date | July 31, 2020 |
Est. primary completion date | July 15, 2019 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Scheduled for elective cardiac surgery either coronary artery bypass grafting and/or valve replacement performed with use of cardiopulmonary bypass Exclusion Criteria: - Left ventricular ejection fraction below 30 percent |
Country | Name | City | State |
---|---|---|---|
Denmark | Dept. of Intensive Care, Aalborg University Hospital | Aalborg |
Lead Sponsor | Collaborator |
---|---|
Aalborg University Hospital | University of Aarhus |
Denmark,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | P/F ratio | Ratio of fraction of inspired oxygen (FiO2) and partial pressure of arterial oxygen (PaO2) | Third postoperative day |
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