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NCT04000893 Clinical Trial

Effect of Aerobic or Resistance Exercise on the Endothelial Response in Post-acute Myocardial Infarction Patients Submitted to Angioplasty

Cardiac Rehabilitation Clinical Trial

Official title:
Effect of Aerobic or Resistance Exercise on the Endothelial Response in Post-acute Myocardial Infarction Patients Submitted to Angioplasty: Randomized Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04000893
Other study ID # AMI and exercise
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date August 1, 2018
Est. completion date June 25, 2019

Study information
Verified date June 2019
Source Instituto de Cardiologia do Rio Grande do Sul
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Cardiac Rehabilitation, as art and acting science multiprofessional, is based on the training with exercises that provides the post-infarct patients to satisfactorily re-establish the patient's clinical condition and that improve the functional capacity of these individuals.

Evidence shows that aerobic exercise training provides improvements in the endothelial function of this population. However, we do not yet have strong evidence of other modalities of exercise in these parameters in post-infarction patients treated with angioplasty.

Recruitment information / eligibility
Status Completed
Enrollment 20
Est. completion date June 25, 2019
Est. primary completion date January 31, 2019
Accepts healthy volunteers No
Gender All
Age group 20 Years to 80 Years
Eligibility Inclusion Criteria:

- Post-acute myocardial infarction patients

- Ergometric test 30 days after the infarction

- Ejection fraction> 40% (Simpson's method)

- Regular use of optimized drugs

Exclusion Criteria:

- Unable to perform the randomized exercise

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• Resistance exercise session
Acute isometric exercise session performed with handgrip Jamar about 20 minutes monitored.

Locations
Country Name City State
Brazil Alexandre Lehnen Porto Alegre Rio Grande Do Sul

Sponsors (1)
Lead Sponsor Collaborator
Instituto de Cardiologia do Rio Grande do Sul

Country where clinical trial is conducted

Brazil, 

Outcome
Type Measure Description Time frame Safety issue
Primary Endothelial function Flow-mediated dilatation technique Pre and post 5 minutes exercise session
Secondary Arterial stiffness Pulse wave velocity technique Pre and post 5 minutes exercise session
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