Cardiac Pacing Indication classI/IIa According AHA/ACC Clinical Trial
Official title:
Progressive Ventricular Dysfunction Prevention in Pacemaker Patients
The purpose of this pilot study is to evaluate the progression of ventricular dysfunction in patients with ventricular dysfunction within the permanent pacing population.
The interventricular synchrony is one of the components of a proper cardiac function. When
there is no synchrony -as in left bundle block (LBBB)- the clinic consequences should have
little importance in patients with a healthy heart or a great importance in patients
suffering heart failure (HF), specially in those with severe grade of HF, the benefit of
cardiac resynchronization by pacing both ventricles or left ventricle (LV)should means
healthy improvement in patients. All previous studies done in HF, are in patients with
symptomatic HF. The importance of stop progression of latent HF in patients with
asymptomatic ventricular dysfunction (VD)in permanent pacing indication patients. Pacing may
accelerate HF progression by dissincronyzing ventricles. ACE inhibitors studies in
asymptomatic VD gave positive results.
The PreVent-HF is an international, multicenter, prospective, randomized, single-blinded
pilot trial specifically designed to evaluate as main objective the progression of VD in
permanent pacing population.
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