Cardiac Output by Nine Different Pulse Contour Algorithms

Status Completed

Clinical Trial Summary

The aim of the present study is to compare accuracy and precision of Cardiac Output (CO) by nine different pulse contour algorithms with transpulmonary thermodilution before and after cardiopulmonary bypass (CPB).

Clinical Trial Description

After induction of anesthesia, a central venous catheter and a transpulmonary thermodilution catheter (Pulsion Medical Systems, Munich, Germany) are introduced in the right internal jugular vein and in the femoral artery, respectively. The thermodilution catheter is connected to a PiCCO2 monitor (Software version 1.3.0.8). Thereafter, placement of an esophageal doppler probe is performed and the probe is connected to a unique Monitoring System (Deltex Medical, Chichester, UK) with nine different pulse contour algorithms. Cardiac Output by esophageal doppler is used to calibrate the nine different pulse contour algorithms.

After induction of anesthesia and establishment of all monitoring devices, a passive leg raising maneouvre (PLR) is performed and hemodynamic variables including CO by transpulmonary thermodilution (COTPTD) and CO by nine different pulse contour algorithms (COX1-9) are recorded before, during and after PLR. Subsequently, measurements of COTPTD and COX1-9 are carried out every 10 minutes until the beginning of CPB. Fifteen minutes after weaning from cardiopulmonary bypass calibration of nine different pulse contour algorithms by esophageal doppler are performed again and measurements of CITPTD and CIPFX are restarted up to the end of the surgical Intervention. ;

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label

Related Conditions & MeSH terms

Cardiac Output

Clinical Trial Details

NCT number	NCT02438228
Study type	Interventional
Source	University of Schleswig-Holstein
Contact
Status	Completed
Phase	N/A
Start date	November 2014
Completion date	November 2015

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT04604886` - The Consistency of Cardiac Output Measured by Pulmonary Artery Catheter and LiDCO in Cardiac Surgical Patients	N/A
Completed	`NCT04044157` - Cardiac Output in Children During Anesthesia
Not yet recruiting	`NCT01678066` - A Prospective Study to Bilaterally Compare a Non-Invasive Cardiac Output Monitor	N/A
Completed	`NCT01001533` - Assess the Ability of Electrical Cardiometry to Trend Hemodynamic Variables During Dexmedetomidine Sedation	N/A
Recruiting	`NCT04926220` - Dynamic Estimation of Cardiac Output in the Operating Room
Not yet recruiting	`NCT06007196` - Evaluation of Non-invasive Continuous Hemodynamic Measurement From Task Force CORE
Recruiting	`NCT05648279` - Personalized Hemodynamic Management in High-risk Major Abdominal Surgery	N/A
Recruiting	`NCT06090396` - Non-invasive Cardiac Index in Children
Completed	`NCT05508711` - Comparability of Transesophageal Echocardiography and FloTrac/Vigileo System Three Different Positions
Withdrawn	`NCT00783679` - The Feasibility and Accuracy of Exhaled CO2 to Measure Cardiac Output in Ventilated Patients Without Tracheal Intubation	N/A
Completed	`NCT00996190` - Best Regimen for Phenylephrine Administration During Cesarean Section	Phase 4
Active, not recruiting	`NCT04465201` - The Smart Pump Study	N/A
Completed	`NCT05779683` - Caretaker in the Cardiovascular Intensive Care Unit (CVICU)
Completed	`NCT04112719` - Assessing Effects of Lateral Tilt on Cardiac Output Using a Non-invasive Technique
Recruiting	`NCT02156856` - Stroke Volume Analysis During Aortic Valve Replacement Trial	N/A
Recruiting	`NCT01781260` - Effect of Prone Position on Liver Blood Flow and Function	N/A
Terminated	`NCT00920569` - Recirculation, Oxygenator Blood Volume and Cardiac Output Measurements During Extracorporeal Membrane Oxygenation	N/A
Recruiting	`NCT06114147` - Cardiac Flow Measurements in Pregnant Women by Non Invasive Techniques	N/A
Completed	`NCT05365113` - Comparison of Hemodynamic Effects of Two Modalities of Alveolar Recruitment Maneuvers in Major Abdominal Surgery Patients	N/A
Completed	`NCT02737813` - Cardiac Output Changes During Hyperbaric and Isobaric Bupivacaine in Patients Undergoing Cesarean Section	Phase 4