Clinical Trials Logo

Clinical Trial Summary

The aim of the present study is to compare accuracy and precision of Cardiac Output (CO) by nine different pulse contour algorithms with transpulmonary thermodilution before and after cardiopulmonary bypass (CPB).


Clinical Trial Description

After induction of anesthesia, a central venous catheter and a transpulmonary thermodilution catheter (Pulsion Medical Systems, Munich, Germany) are introduced in the right internal jugular vein and in the femoral artery, respectively. The thermodilution catheter is connected to a PiCCO2 monitor (Software version 1.3.0.8). Thereafter, placement of an esophageal doppler probe is performed and the probe is connected to a unique Monitoring System (Deltex Medical, Chichester, UK) with nine different pulse contour algorithms. Cardiac Output by esophageal doppler is used to calibrate the nine different pulse contour algorithms.

After induction of anesthesia and establishment of all monitoring devices, a passive leg raising maneouvre (PLR) is performed and hemodynamic variables including CO by transpulmonary thermodilution (COTPTD) and CO by nine different pulse contour algorithms (COX1-9) are recorded before, during and after PLR. Subsequently, measurements of COTPTD and COX1-9 are carried out every 10 minutes until the beginning of CPB. Fifteen minutes after weaning from cardiopulmonary bypass calibration of nine different pulse contour algorithms by esophageal doppler are performed again and measurements of CITPTD and CIPFX are restarted up to the end of the surgical Intervention. ;


Study Design

Intervention Model: Single Group Assignment, Masking: Open Label


Related Conditions & MeSH terms


NCT number NCT02438228
Study type Interventional
Source University of Schleswig-Holstein
Contact
Status Completed
Phase N/A
Start date November 2014
Completion date November 2015

See also
  Status Clinical Trial Phase
Recruiting NCT04604886 - The Consistency of Cardiac Output Measured by Pulmonary Artery Catheter and LiDCO in Cardiac Surgical Patients N/A
Completed NCT04044157 - Cardiac Output in Children During Anesthesia
Not yet recruiting NCT01678066 - A Prospective Study to Bilaterally Compare a Non-Invasive Cardiac Output Monitor N/A
Completed NCT01001533 - Assess the Ability of Electrical Cardiometry to Trend Hemodynamic Variables During Dexmedetomidine Sedation N/A
Recruiting NCT04926220 - Dynamic Estimation of Cardiac Output in the Operating Room
Not yet recruiting NCT06007196 - Evaluation of Non-invasive Continuous Hemodynamic Measurement From Task Force CORE
Recruiting NCT05648279 - Personalized Hemodynamic Management in High-risk Major Abdominal Surgery N/A
Recruiting NCT06090396 - Non-invasive Cardiac Index in Children
Completed NCT05508711 - Comparability of Transesophageal Echocardiography and FloTrac/Vigileo System Three Different Positions
Withdrawn NCT00783679 - The Feasibility and Accuracy of Exhaled CO2 to Measure Cardiac Output in Ventilated Patients Without Tracheal Intubation N/A
Completed NCT00996190 - Best Regimen for Phenylephrine Administration During Cesarean Section Phase 4
Active, not recruiting NCT04465201 - The Smart Pump Study N/A
Completed NCT05779683 - Caretaker in the Cardiovascular Intensive Care Unit (CVICU)
Completed NCT04112719 - Assessing Effects of Lateral Tilt on Cardiac Output Using a Non-invasive Technique
Recruiting NCT02156856 - Stroke Volume Analysis During Aortic Valve Replacement Trial N/A
Recruiting NCT01781260 - Effect of Prone Position on Liver Blood Flow and Function N/A
Terminated NCT00920569 - Recirculation, Oxygenator Blood Volume and Cardiac Output Measurements During Extracorporeal Membrane Oxygenation N/A
Recruiting NCT06114147 - Cardiac Flow Measurements in Pregnant Women by Non Invasive Techniques N/A
Completed NCT05365113 - Comparison of Hemodynamic Effects of Two Modalities of Alveolar Recruitment Maneuvers in Major Abdominal Surgery Patients N/A
Completed NCT02737813 - Cardiac Output Changes During Hyperbaric and Isobaric Bupivacaine in Patients Undergoing Cesarean Section Phase 4