Immune Correlates of Cardiac Structure and Function

Cardiac Fibrosis Clinical Trial

Official title: Immune Correlates of Cardiac Structure and Function

Status Completed

Clinical Trial Summary

The purpose of this study is to determine the occurrence of scarring of the heart (cardiac fibrosis) and inflammation in those with perinatally acquired Human Immunodeficiency Virus (HIV) infection compared to people not infected with HIV. The information learned from this research may help the investigator to better understand the link between cardiac fibrosis and cardiac dysfunction and inflammation in those with perinatally acquired HIV infection compared to the uninfected.

Participants will have a blood sample, complete a patient questionnaire, and have a Magnetic resonance imaging (MRI) and ultrasound of the heart.

Researchers will review the medical record and past medical history, for information about your heart function and overall health. Research samples and data from this study will be stored indefinitely and used for other research.

There are risks to participate in this study and those risks include side effects from the contrast agent used for the MRI scan, (such as headache and injection site pain), and risks from blood sampling.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Cardiac Fibrosis
• Cardiac Inflammation
• Inflammation
• Perinatal HIV Infection

• NCT number: NCT05328713
• Study type: Observational
• Source: Duke University
• Status: Completed
• Start date: May 9, 2022
• Completion date: September 21, 2022