Near Infrared Spectroscopy (NIRS) for Heart Failure Assessment.

Status Recruiting

Clinical Trial Summary

It is routine practice for a cardiologist to perform a battery of tests to assess the degree of heart failure. The purpose of this study is to establish a non-invasive method to reliably predict cardiac output state in real-time in children and adolescents with heart failure in an outpatient setting. This study will rely on the use of near infrared spectroscopy monitors to measure cardiac output in the outpatient setting.

Clinical Trial Description

Near-infrared spectroscopy (NIRS) technology, such as that used in pulse oximetry, has been used in medicine for decades. Several characteristics contribute to its widespread use, including its noninvasive nature, reliability and safety. The Somanetics' INVOS® System harnesses this power to safely and reliably "see inside" the brain and body. NIRS devices measure the venous weighted oxy-hemoglobin saturation (color of blue blood) in a field of tissue, rather than in arteries, and thus the rSO2 parameter provides a window into regional oxygen supply-demand relationships. Monitoring rSO2 at two distinct sites (cerebral and somatic) has become common practice at our institution for all infants and children in the intensive care unit and provides valuable feedback about potentially deleterious trends in regional tissue oxygenation that cannot easily be obtained by other modalities in such patients. ;

Study Design

Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01577810
Study type	Interventional
Source	Phoenix Children's Hospital
Contact	Rohit Rao, MD
Phone	(262)309-4874
Email	rrao@phoenixchildrens.com
Status	Recruiting
Phase	N/A
Start date	June 2013
Completion date	August 2014

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT03799133` - Safety and Efficacy of the Gastric Reactance (XL) in Patients Post-operated of Elective Cardiac Surgery	N/A
Not yet recruiting	`NCT04538469` - Absent Visitors: The Wider Implications of COVID-19 on Non-COVID Cardiothoracic ICU Patients, Relatives and Staff
Terminated	`NCT02205411` - Clinical Trial to Evaluate the the ReliantHeart HeartAssist 5® VAD System in Patients Awaiting Heart Transplantation	N/A
Completed	`NCT02524574` - Tomography Positron Emission Assessment of the Impact of Cardiac Rehabilitation on Coronary Endothelial Function in Cardiac Failure	N/A
Active, not recruiting	`NCT03841084` - Blend to Limit Oxygen in ECMO: A Randomised Controlled Registry Trial	Phase 2
Terminated	`NCT02459054` - Syncardia 50cc TAH-t as a Bridge to Transplant	N/A
Terminated	`NCT02859636` - Pronostic Value of Endothelial Dysfunction in Heart Failure	N/A
Completed	`NCT04599816` - Levosimendan Administration in Pulmonary Hypertension	N/A
Recruiting	`NCT05761639` - Physical Exercise and Telephone Follow-up Mediated by Telerehabilitation	N/A
Not yet recruiting	`NCT04696523` - Effect of Xenon on Brain Injury After Aneurysmal Subarachnoid Hemorrhage	Phase 2
Completed	`NCT03357731` - A Study of Continuous Infusions of HNO (Nitroxyl) Donor in Patients With Heart Failure and Impaired Systolic Function	Phase 2
Completed	`NCT02331264` - Cardiac Assessment of Patients With Hip Implants	N/A
Terminated	`NCT01921829` - Protocolized Diuretic Strategy in Cardiorenal Failure	Phase 4
Completed	`NCT06197256` - Cardiac Dysfunction in Critically Ill Covid-19 Patients
Recruiting	`NCT03197792` - Perioperative Portal Vein Pulsatility as a Postoperative Prognostic Indicator in Pulmonary Endarterectomy	N/A
Completed	`NCT03515980` - An Investigational Study of Experimental Medication BMS-986231 Given in Participants With Different Levels of Liver Function	Phase 1
Completed	`NCT03212898` - Pharmacist Interventions in Rural Elderly Warfarin Patients	N/A
Completed	`NCT03243604` - cARdiotoxicity Profile of aBIraTeRone in prostAte Cancer : a pharmacoviGilancE Study
Completed	`NCT06330103` - Efficacy of AI EF Screening by Using Smartphone Application Recorded PLAX View Cardiac Ultrasound Video Clips	N/A
Completed	`NCT02660385` - Insomnia Self-Management in Heart Failure	N/A