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Cardiac Event clinical trials

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NCT ID: NCT02870660 Recruiting - Clinical trials for Acute Coronary Syndrome

Familial Hypercholesterolemia Amongst Patients With Acute Coronary Syndrome

Start date: August 2016
Phase: N/A
Study type: Observational [Patient Registry]

Familial hypercholesterolemia (FH) is a most prevalent genetic disorder, defines as high cholesterol level and premature death. The prevalence of FH has been reported in few countries however unknown in Iran. Thus recognize the FH patients, determine the diagnostic strategies and appropriate treatments are important. Also acute coronary syndrome (ACS) is a group of conditions which arises from reduction of blood flow in coronary arteries. Three specific conditions are included: ST elevation myocardial infarction, non ST elevation myocardial infarction and unstable angina. Premature ACS defined by occurrence of ACS<55 for men and ACS<60 for women. Studies demonstrated direct connection between familial hypercholesterolemia and occurrence of premature ACS. Investigators intent to detection of FH amongst patients with acute coronary syndrome.

NCT ID: NCT02850250 Withdrawn - Cardiac Event Clinical Trials

Pharmacokinetics of Post Operative Cefuroxime in Infants Undergoing Cardiac Surgery

PHOXEY
Start date: July 2018
Phase:
Study type: Observational

- To evaluate plasma concentrations of Cefuroxime in this patient population - To determine if certain pathophysiological and/or iatrogenic conditions alter the pharmacokinetics in this patient group. - To develop a rational physiological population pharmacokinetic model that describes plasma concentrations of medications in these patients.

NCT ID: NCT02814084 Completed - Cardiac Event Clinical Trials

Prevena Incision Management

Prevena
Start date: September 13, 2016
Phase: N/A
Study type: Interventional

The question this research project wants to explore is whether using the Prevena Incision Management System (Prevena) will improve sternal wound edge oxygenation in patients undergoing Coronary Artery bypass surgery with Bilateral Internal Mammary Artery grafts.

NCT ID: NCT02778646 Completed - Clinical trials for Percutaneous Coronary Intervention

Detection of Familial Hypercholesterolaemia in Cardiovascular Disease Registry

Start date: January 2003
Phase: N/A
Study type: Observational [Patient Registry]

Familial hypercholesterolaemia (FH) is an autosomal dominant somatic mutation commonly located on the LDL-receptor, APOB, and PCKS9 gene. The estimated prevalence of homozygous FH is estimated at 1 in a million, whereas the prevalence of heterozygous FH ranges from 1/500-1/200 (0.2-0.5%) of the general population. The majority of individuals suffering from FH remain undiagnosed and without treatment. Using preexisting clinical guidelines, this study scored patients within national cardiovascular disease (CVD) registries for FH with the aim of evaluating prevalence of FH among individuals suffering from premature cardiac events within the UK. Following scoring of the registry, this study also examined the relationship between cholesterol and survival after a premature event in order to understand the possible ramifications of untreated FH on patient survival.

NCT ID: NCT01830023 Completed - Cardiac Event Clinical Trials

Vitality Trial - Sampling Examination Data

Start date: May 2009
Phase: N/A
Study type: Observational

This study´s aim is to collect data of vitality diagnosis. A cardiac ultrasound examination will be done and the data will be compared to the other examinations.

NCT ID: NCT01776333 Not yet recruiting - Respiratory Failure Clinical Trials

A Randomized Controlled Trial of a Video Decision Aid in the ICU

VIDEO
Start date: January 2013
Phase: N/A
Study type: Interventional

Randomized Controlled Trial of a Video Decision Aid in the ICU in surrogates of admitted patients.

NCT ID: NCT01675063 Active, not recruiting - Cardiac Event Clinical Trials

Minimally Invasive Cardiac Output Monitoring Device

Start date: August 2012
Phase: N/A
Study type: Interventional

The overall goal of this collaborative study is to advance the novel "pulse contour analysis" to the point at which it can be incorporated into a real-time device. The specific objective is to establish an auto-calibration algorithm that conveniently yields cardiac output (CO) in units of liters-per-minute. To achieve this objective, the waveforms for analysis and reference pulmonary artery catheter CO measurements will be recorded from critically ill patients and then analyzed off-line at Retia Medical. Successful completion of this study may ultimately help lead to improved outcomes of critically ill patients.

NCT ID: NCT01665755 Completed - Clinical trials for Ventricular Tachycardia

To Determine Optimal Time for Delivering Electrical Shocks to Cardiac Arrest Patients

Start date: January 2016
Phase: N/A
Study type: Interventional

In this study, we are comparing the difference in outcomes between patients who were given shocks to the heart, during the upstroke of cardiopulmonary resuscitation (CPR) and before CPR is started. The study population will be all cardiac arrest patients attended by the staff of the Emergency Department who fulfil the eligibility criteria. Patients will be managed according to currently approved cardiac arrest protocols. Patients confirmed in cardiac arrest have manual chest compressions started while mechanical CPR (whereby chest compressions are delivered by an automated device) is prepared. Mechanical CPR should be started as soon as possible (<1 minute). If patients are eligible to be shocked, they will receive shocks either during upstroke of CPR or before CPR is started. Thus the purpose of this study is to answer the question whether are there improvement in survival between when shocks are given during upstroke and before CPR is started.

NCT ID: NCT00750958 Completed - Cardiac Event Clinical Trials

PREVENT - Prospective Rhythm Event Surveillance in the ER With NetGuard

PREVENT
Start date: June 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the incidence of clinically significant rhythm and rate changes in ED patients who are not placed on conventional telemetry, and to test the user-friendliness of a automated clinician alter device in hectic and noisy setting of a busy emergency room.