Clinical Trials Logo
  1. Home
  2. Cardiac Disease
  3. NCT05258448

COr Loco-regional Advanced Lung Cancer Treated With Chemo-radiotherapy (COLA) — COLA  

Cardiac Disease Clinical Trial

Official title:
The Effect of Radiotherapy on the Heart in Loco-regional Advanced NSCLC Patients Treated With Definitive Radiotherapy Measured by Cardiac MR

Clinical Trial Summary

Patients with loco-regional NSCLC planned for curative treatment with chemoradiotherapy will be invited to participate in a prospective study; besides routine treatment, the patients will be followed with an ECG and cardiac MR for at least two years after radiotherapy treatment.

Clinical Trial Description

Definitive chemo-radiotherapy is the treatment of choice for loco-regional advanced non-small cell lung cancer (LA-NSCLC). However, the treatment is associated with a range of side effects with radiation pneumonitis and esophagitis. In addition, the toxicity of the heart in lung cancer patients treated with radiotherapy has been offered less consideration. Therefore, it is essential to investigate the possible early and late toxicity to the heart and the baseline cardiac status of these patients. This study will describe cardiac comorbidity before radiotherapy treatment by a thorough history. Furthermore, we will evaluate heart function and evaluate possible heart disease by an ECG and cardiac MR. Patients will be followed with ECG and cardiac MR for two years after radiotherapy, detecting structural changes caused by radiotherapy and subclinical disease after radiotherapy. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05258448
Study type Observational [Patient Registry]
Source Odense University Hospital
Contact Agon AO Olloni, MD
Phone 42206617
Email agon.olloni@rsyd.dk
Status Recruiting
Phase
Start date August 2015
Completion date October 2026
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05490303 - HeartGuide: Preliminary Study N/A
Completed NCT05070819 - Atrial Natriuretic Peptide in Assessing Fluid Status N/A
Not yet recruiting NCT04511403 - Prevalence of Oral Mucosal Alterations In a Sample of Egyptian Patients With Cardiovascular Diseases: A Hospital- Based Cross-Sectional Study
Not yet recruiting NCT04538469 - Absent Visitors: The Wider Implications of COVID-19 on Non-COVID Cardiothoracic ICU Patients, Relatives and Staff
Completed NCT02697760 - The CZT Dynamic Myocardial Perfusion Imaging
Terminated NCT05157568 - Pilot Randomized Clinical Trial of Live-streamed Cardiovascular Rehabilitation N/A
Not yet recruiting NCT04160845 - Non-invasive Forehead Skin Temperature in Cardiac Surgery
Completed NCT04500912 - Comparison of the Supraflex Cruz 60 Micron Versus the Ultimaster Tansei 80 Micron in HBR PCI Population N/A
Not yet recruiting NCT06438159 - Impact of Mindfulness-Based Stress Reduction Meditation Practice on Patients After Cardiac Rehabilitation. N/A
Recruiting NCT06154473 - Assessment of Patients Undergoing Cardiac Surgery and Admitted to the Intensive Care Unit
Not yet recruiting NCT05877755 - Validation of Multi-contrast, High-resolution Cardiac Magnetic Resonance Imaging N/A
Completed NCT03394859 - Electronic Medical Records and Genomics (eMERGE) Phase III
Recruiting NCT05055830 - Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)
Recruiting NCT04374799 - Heparin vs Placebo for Cardiac Catheterization Phase 3
Completed NCT03174106 - Longterm Follow-up of Cardiac Patients With an Smartphone-Application N/A
Recruiting NCT05531253 - Respired Gases in Patients Post Cardiac Surgery
Recruiting NCT04609228 - Cardiac Surgery Outcomes in Blood-transfusion Acceptors and no Acceptors
Recruiting NCT06149143 - Cardiac Performance System Data Collection Study - Minnesota
Recruiting NCT05725655 - Hot Water Immersion After Myocardial Infarction N/A
Recruiting NCT06073509 - Atrial Fibrillation and Other Cardiac Arrhythmias and Diseases After Radiotherapy for Breast Cancer : Watch Your HeaRT