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Myocardial Perfusion and Scarring in Adults With Congenital Heart Disease

Cardiac Disease Clinical Trial

Official title:
Quantitative Myocardial Perfusion, Myocardial Scarring and Their Contribution to Late Clinical Decompensation in Adults With Congenital Heart Disease

Clinical Trial Summary

This is a study of the perfusion of the myocardium in adults with specific forms of repaired congenital heart disease using established cardiac MRI techniques and correlating perfusion with clinical outcomes.

Clinical Trial Description

This is a study of the perfusion of the myocardium in adults with specific forms of repaired congenital heart disease using established cardiac MRI techniques and correlating perfusion with clinical outcomes. The investigators objectives are to examine myocardial perfusion both during stress and at rest in adults with repaired or palliated congenital heart disease as well as quantify ventricular function, regional myocardial strain and evidence of myocardial fibrosis with quantitative measures of myocardial perfusion. The specific aim of this study is to understand whether clinical subendocardial perfusion defects contribute to the late decompensation of adult subjects that have single ventricle physiology and adult subjects that have a systemic right ventricle. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02861365
Study type Observational
Source Children's National Research Institute
Contact
Status Completed
Phase
Start date July 2013
Completion date January 18, 2020
View Details
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