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Cardiac Disease clinical trials

View clinical trials related to Cardiac Disease.

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NCT ID: NCT06379503 Completed - Cardiac Disease Clinical Trials

Effect of Heart Yoga Applıed To Patıents Undergoıng Cardıovascular Surgery on Sleep, Depressıon And Qualıty of Lıfe

Start date: December 15, 2021
Phase: N/A
Study type: Interventional

This type of study is a randomized controlled trial. The aim is to contribute to the literature by comparing the effects of heart yoga on the depression level, sleep and quality of life of patients who do and do not do heart yoga. The main elements it aims to answer are: - Heart yoga applied to patients who have undergone heart surgery improves their sleep quality compared to those who have not. - Heart yoga applied to patients who have undergone heart surgery reduces the level of depression compared to those who have not. - Heart yoga applied to patients who have undergone heart surgery increases the quality of life compared to those who have not. Patients who accept the study will practice heart yoga simultaneously with heart yoga videos via an online link every other day for 12 weeks after heart surgery. Researchers will compare intervention and control groups to see if there are any effects on sleep quality, depression level, and quality of life.

NCT ID: NCT06027164 Completed - Cardiac Disease Clinical Trials

Kosmos Trio and Ejection Fraction Pivotal Study

Start date: August 4, 2023
Phase:
Study type: Observational

This is a single-group, observational study which will involve obtaining two echo scans of recruited patients. All recruited patients will undergo echo scans by both novice users (nurses) and experts (echo sonographers). Image quality between novices and experts as well as the ability to calculate LVEF from novice and expert scans and the quality of the LVEF calculated via KOSMOS-EF compared to LVEF calculations by expert cardiologists will occur in post-hoc Echo image analysis

NCT ID: NCT05942183 Completed - Cardiac Disease Clinical Trials

Optic Nerve Sheath Diameter is Associated With Postoperative Delirium in Patients Undergoing Open Heart Surgery

Start date: August 7, 2023
Phase:
Study type: Observational

Although the incidence of delirium after cardiac surgery is high, it is not sufficiently recognized. The long-term effects of delirium are likely to be underestimated. In this study, the investigators aimed to examine the relationship between optic nerve sheath diameter and postoperative delirium in open hearth surgery.

NCT ID: NCT05880615 Completed - Cardiac Disease Clinical Trials

Opioid Reduced Anesthesia With Parasternal CATheters on Postoperative Delirium After Cardiac Surgery

ORACAT
Start date: May 2, 2022
Phase:
Study type: Observational

PostOperative Delirium (POD) is the most common neuropsychiatric complication following cardiac surgery and may be related to morphine consumption. PostOperative Delirium (POD) prolongs hospital and intensive care unit (ICU) length of stay (LOS) and increases morbidity and mortality. No study has been conducted to demonstrate the effect of regional anesthesia using catheters inserted before sternotomy.

NCT ID: NCT05780125 Completed - Surgery Clinical Trials

Effectiveness of Different Fibrinogen Preparations in Restoring Clot Firmness

EDIPORE
Start date: March 20, 2023
Phase: Phase 2
Study type: Interventional

Fibrinogen concentrate is produced by different manufacturers using different purification technologies. The products available in Italy are three: RiaSTAP (CSL Behring), FIBRYGA (Octapharma), and FibCLOT (LFB). RiaSTAP and FIBRYGA are sold in 1-gram vials, and FibCLOT - in 1.5-gram vials. A recent in vitro study assessed how these products affected the clot firmness measured by the ROTEM FIBTEM maximum clot firmness (MCF) parameter. In vitro conditions, FibCLOT was verified to be the most efficient in increasing clot firmness. The present study is aimed to assess, in a series of patients undergoing cardiac surgery with cardiopulmonary bypass, the hypothesis that the FibCLOT fibrinogen is superior to the RiaSTAP fibrinogen in increasing the FIBTEM MCF parameter in a clinical model of bleeding (postoperative bleeding after complex cardiac surgery).

NCT ID: NCT05764616 Completed - Surgery Clinical Trials

Parasternal Block Combined With Rectus Sheath Block for Cardiac Surgery Under Sternotomy

PARARECTUS
Start date: March 21, 2023
Phase: N/A
Study type: Interventional

The aim of this randomized controlled trial is to examine the effect of ultrasound guided bilateral Parasternal Nerve Block combined with rectus sheath block on preoperative analgesia, opioid consumption and respiratory function in patients undergoing cardiac surgery via sternotomy. Half of participants will receive General Anesthesia combined with bilateral parasternal block and rectus sheath block while the other half receive General Anesthesia combined with bilateral parasternal block and infiltration of drainage exits sites with local anesthetic (without performing rectus sheath block)

NCT ID: NCT05749744 Completed - Cardiac Disease Clinical Trials

Effects of Cardiac Telerehabilitation During COVID-19 on Cardiorespiratory Capacities in Coronary Artery Disease Patients.

Start date: March 1, 2021
Phase:
Study type: Observational

After an acute coronary syndrome, an adapted cardiac rehabilitation program is necessary to restore or increase physical capacities and decrease cardiovascular risk. This multidisciplinary care combines physical training sessions and therapeutic education workshops. The COVID-19 pandemic imposed restrictions such as the closure of rehabilitation centres. To remedy this problem, one solution was to adapt the existing program to a remote cardiac telerehabilitation, i.e., medical and paramedical supervision of rehabilitation sessions and therapeutic patient education meetings via digital tools. Recent studies have shown that it was a safe (no reported adverse effects), effective (similar gains in peak oxygen consumption compared to traditional cardiac rehabilitation and patient-adherence alternative.

NCT ID: NCT05742789 Completed - Cardiac Disease Clinical Trials

Effect of Anesthetics on Troponin I and С-reactive Protein

Start date: November 30, 2021
Phase: Phase 1
Study type: Interventional

Abstract Troponin is one of the cardiac biomarkers and its high level correlates to high risk of cardiac myocytes damage. C-reactive protein (CRP) in cardiosurgery participates in the Systemic Inflammation Response Syndrome, and heart-lung apparatus is a powerful stimulator of the systemic inflammatory reaction. Objective: To assess effect of anesthetics on troponin I and СRP in mitral, tricuspid and aortic valve replacement/plastic in adult. Methods. Single-center prospective randomized controlled clinical study. A total of 95 patients were assigned randomly into three groups according to the type of anesthesia: the first group of 32 patients with propofol, the second group with sevoflurane - 32 patients, and the last - 31 patients were with isoflurane. Levels of the cardiac troponin I were calculated in ng/ml с using a portable fluorometric analyzer I-CHROMAII, manufacture of BoditechMedInc (South Korea). Normal range: <0.04 ng/ml. CRP concentration in plasma has been determined using a biochemical analyzer Biosystems BA-200 (Spanish company, Barcelona) according to the manufacturer's instructions. The normal level of CRP is less than 5 mg/l.

NCT ID: NCT05698121 Completed - Cardiac Disease Clinical Trials

Evaluation of a Preparatory eHealth Intervention to Support Cardiac Patients During Their Waiting Period.

PReCARE
Start date: February 8, 2023
Phase: N/A
Study type: Interventional

The goal of this pilot study is to evaluate the feasibility of an eHealth intervention for cardiac patients during their waiting period before their rehabilitation. The main questions it aims to answer are: - What is the feasibility of an eHealth intervention designed for cardiac patients with a low socio-economic position during the waiting period before their cardiac rehabilitation. - What is the potential effect of this intervention on patient activation and feelings of certainty and guidance. Participants will: - Be randomised in either intervention or control group - Fill in a questionnaire at the start of their waiting period (after release from the hospital) - Use the eHealth intervention during their waiting period (usually 2 to 6 weeks)(intervention group only) - Fill in a questionnaire at the start of their rehabilitation Researchers will compare intervention and control group to see if the intervention has improved patient activation and feelings of certainty and guidance.

NCT ID: NCT05660044 Completed - Cardiac Disease Clinical Trials

Human Factors Study of Ultrasound Navigation Software for Cardiac Imaging

Start date: July 20, 2022
Phase:
Study type: Observational

The Product is a machine learning software, that utilizes AI to provide real-time guidance to acquire diagnostic-quality ultrasound views of the heart.