Clinical Trials Logo
  1. Home
  2. Cardiac Arrhythmias
  3. NCT05450302

Assessing the Predictive Value of High Frequency Algorithm of PURE EP for Low Amplitude Signal Detection

Cardiac Arrhythmias Clinical Trial

Official title:
To Assess the Predictive Value of High Frequency Algorithm of PURE EP for Low Amplitude Signal Detection

Clinical Trial Summary

Prior multicenter study demonstrated superiority of PURE EP to conventional mapping. This superiority was seen when comparing small, fractionated signals of interest, near-field vs far-field distinction, and general signal quality (2). Hence, investigators propose a retrospective study to assess the predictive value of high frequency algorithm (HFA) for identifying local physiologic signal under 0.3 mV distinctive of noise.

Clinical Trial Description

Accurate interpretation of intracardiac EGMs remains essential to the field of electrophysiology (EP). Conventional Electro-anatomical mapping systems (EAMs) have made significant improvements in EGM quality and noise reduction since their emergence, however their use of variable gain amplifiers and high/low pass filters, often provide visualization of low amplitude signals that lead to saturation artifact or necessitate signal clipping. PURE EPTM (BioSig Technologies, Inc., Westport, CT, USA), in contrast does provide the ability to record this unaltered signal with more customizable display options. Their proprietary amplifier and high-resolution analog-digital converters with Radiofrequency (RF) suppression eliminates the need for gain switching, optimizing resolution of the full range of input signals (1). Prior multicenter study demonstrated superiority of PURE EP to conventional mapping. This superiority was seen when comparing small, fractionated signals of interest, near-field vs far-field distinction, and general signal quality (2). Hence, investigators propose a retrospective study to assess the predictive value of high frequency algorithm (HFA) for identifying local physiologic signal under 0.3 mV distinctive of noise. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05450302
Study type Observational
Source Kansas City Heart Rhythm Research Foundation
Contact Donita Atkins
Phone 816-651-1969
Email Datkins@kchrf.com
Status Not yet recruiting
Phase
Start date April 2023
Completion date December 2023
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05175937 - REal World Assessment for Patients Implanted With Implantable CardioverTer DefibrIllatOr Using Bluetooth Technology
Not yet recruiting NCT05005143 - Improved Procedural Workflow For Catheter Ablation Of Paroxysmal AF With High Density Mapping System And Advanced Technology
Completed NCT02684825 - Detection of Silent Atrial Fibrillation aFter Ischemic StrOke N/A
Terminated NCT01936480 - Genetics of QT Response to Moxifloxacin Phase 4
Completed NCT01719978 - Hemodynamic and Electrocardiographic Effects of Hyaluronidase Associated With Local Anaesthetics Phase 4
Completed NCT00418314 - FREEDOM - A Frequent Optimization Study Using the QuickOpt Method N/A
Completed NCT04361006 - Cryotherapy Versus Radiofrequency Ablation for Treatment of Para-hisian Accessory Pathways N/A
Completed NCT02326519 - Electrical Signal Collection From a 20 Pole Catheter During Routine Cardiac Procedures N/A
Completed NCT01642537 - Electroanatomical Mapping of Patients Undergoing Catheter Ablation Procedures Using Rhythmia Mapping System and Catheter N/A
Completed NCT01509378 - 4P Study: Predictive Quality With Painfree Therapies N/A
Completed NCT02698670 - Prospective Registry on User Experience With The Mapping System For Ablation Procedures N/A
Recruiting NCT01566344 - Reversal of Cardiomyopathy by Suppression of Frequent Premature Ventricular Complexes N/A
Recruiting NCT03793998 - Catheter Ablation of Arrhythmias With High Density Mapping System in the Real World Practice.
Active, not recruiting NCT03110627 - Increasing Detection of Sub-Clinical Atrial Fibrillation in Defibrillator Patients With the Use of a VDD-ICD Lead N/A
Recruiting NCT05771142 - Evaluation of an Innovative Smart T-shirt Capable to Monitor ECG Signal and Related Parameters Through the Comparison With a Holter ECG and a Smartwatch
Not yet recruiting NCT02657590 - Documentation of Cardiac Arrhythmias After Open Heart Surgery N/A
Completed NCT02080975 - Determination of Catheter Contact by Evaluation of Microelectrode Near-Field Signals N/A
Recruiting NCT05724121 - Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax
Completed NCT02332096 - Screening for Sleep Apnea in Patients Undergoing Atrial Fibrillation Ablation
Completed NCT01946776 - Cardiac Arrhythmias in Epilepsy: the CARELINK-study N/A