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Clinical Trial Summary

The purpose of this pilot interventional study is to collect preliminary data on administering packed red blood cell (PRBC) during cardiac arrest (CA). The primary objective is to assess the feasibility of PRBC transfusion during cardiac CA to help optimize the methods required to augment cerebral and other vital organ oxygen delivery during cardiopulmonary resuscitation (CPR). The secondary objectives are to assess the effect of PRBC transfusion during prolonged cardiac arrests on cerebral oxygenation, end tidal carbon dioxide (ETCO2), return of spontaneous circulation (ROSC), survival to discharge, biomarkers of neural injury and inflammation, and neurological outcomes at hospital discharge, 30 days post-CA, and 90 days post-CA.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06462027
Study type Interventional
Source NYU Langone Health
Contact Anelly Gonzales
Phone 646-501-6923
Email resuscitationlab@nyulangone.org
Status Not yet recruiting
Phase Phase 1
Start date August 1, 2024
Completion date April 1, 2026

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