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Sedation, Temperature and Pressure After Cardiac Arrest and Resuscitation — STEPCARE  

Hypoxia, Brain Clinical Trial

Official title:
Sedation, Temperature and Pressure After Cardiac Arrest and Resuscitation

Clinical Trial Summary

The STEPCARE-trial is a 2x2x2 randomised trial studying patients who have been resuscitated from cardiac arrest and who are comatose. It will include three different interventions focusing on sedation targets, temperature targets and mean arterial pressure targets.

Clinical Trial Description

3500 patients who are comatose after cardiac arrest will be included in a trial studying three separate targets. All patients will be randomised to a control or an intervention arm for sedation, temperature and blood pressure targets. These are. 1. Continuous deep sedation for 36 hours or minimal sedation (SEDCARE) 2. Fever management with or without a feedback-controlled device (TEMPCARE) 3. A mean arterial pressure target of >85mmHg or >65mmHg. (MAPCARE) Participants will be followed up at 30 days and 6 months. The primary outcome will be survival at 6 months. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05564754
Study type Interventional
Source Region Skane
Contact Josef Dankiewicz, PhD
Phone +464671000
Email josef.dankiewicz@med.lu.se
Status Recruiting
Phase N/A
Start date August 17, 2023
Completion date June 2026
View Details
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