Prophylactic Amiodarone for Shockable Cardiac Arrest

Status Recruiting

Clinical Trial Summary

The aim of this study is to determine whether the prophylactic amiodarone can prevent re-arrest with ventricular shockable rhythm in patients who treated with targeted temperature management after return of spontaneous circulation from cardiac arrest which had been shockable rhythm during CPR.

Clinical Trial Description

Patients with cardiac arrest are in high risk of re-arrest during post cardiac arrest care due to vulnerable heart state electrically and hemodynamically. Especially if patients who had experienced shockable rhythms such as ventricular fibrillation or pulseless ventricular tachycardia during CPR, then they are at high risk of developing shockable re-arrest. However until now there has not been any evidence of prophylactic anti arrhythmic drug effect during post cardiac arrest care. Amiodarone is class III anti arrhythmic drug which has been used for conversion of ventricular arrhythmia during CPR. In this study we want to determine whether the prophylactic amiodarone can prevent re-arrest with ventricular shockable rhythm or not. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04845607
Study type	Interventional
Source	Asan Medical Center
Contact
Status	Recruiting
Phase	Phase 3
Start date	April 1, 2021
Completion date	February 28, 2023

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