Infant Chest Compression

Cardiac Arrest Clinical Trial

Official title:

Impact of Newly Infant Chest Compression Technique on Hemodynamic Effect During CPR: A Multicenter Randomized Crossover Experimental Study

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03616938
• Other study ID #: NLS_2018_UL
• Status: Recruiting
• Phase: N/A
• Start date: July 28, 2018
• Est. completion date: August 2018

Study information

• Verified date: August 2018
• Source: Lazarski University
• Contact: Lukasz Szarpak, PhD
• Phone: 500186225
• Email: lukasz.szarpak[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

our aim was to quantitatively compare the quality of chest-compression of the new two thumb chest compression (nTTT) versus the current standard techniques: two finger technique (TFT), two thumb technique (TTHT) as defined by systolic-, diastolic-, mean arterial- and pulse-pressures. Our hypothesis is that nTTT generates higher arterial blood pressures compared to the established TFT and TTHT in an infant manikin model.

Description:

To simulate the scenario of infant CPR, an ALS Baby trainer manikin (Laerdal Medical, Stavanger, Norway) simulating a 3-month-old infant. The manikin was connected with a fixed-volume arterial system attached to a monitor (Draeger Infinity® Delta; Draegerwerk AG & Co. KGaA, Luebeck, Germany) via an arterial pressure transducer (Edward Lifesciences: TruWave Disposable Pressure Transducer; Irvine, CA, USA). The arterial circuit composed of a 50-mL bag of normal saline solution (air removed) attached to the manikin chest plate and connected to the transducer with a 20-gauge intravenous catheter and tubing. The manikin was placed on a high adjustable hospital stretcher. The bed was leveled to the iliac crest of each rescuer for standardization. The manikin was previously intubated and ventilation was performed using a resuscitator bag.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 65
• Est. completion date: August 2018
• Est. primary completion date: August 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• nurses

• give voluntary consent to participate in the study

Exclusion Criteria:

• not meet the above criteria

• wrist or low back diseases

Related Conditions & MeSH terms

• Cardiac Arrest
• Heart Arrest
• Infant
• Simulation

Intervention

Procedure:
• Cardiopulmonary resuscitation
2-min cycle of cardiopulmonary resuscitation accorind to the American Heart Association 2015 guidelines

Locations

Country	Name	City	State
Poland	Faculty of Medicine, Lazarski University	Warsaw	Masovian

Sponsors (2)

Lead Sponsor	Collaborator
Lukasz Szarpak	Wroclaw Medical University

Country where clinical trial is conducted

Poland, 

References & Publications (3)

Ladny JR, Smereka J, Rodríguez-Núñez A, Leung S, Ruetzler K, Szarpak L. Is there any alternative to standard chest compression techniques in infants? A randomized manikin trial of the new "2-thumb-fist" option. Medicine (Baltimore). 2018 Feb;97(5):e9386. doi: 10.1097/MD.0000000000009386. — View Citation

Smereka J, Szarpak L, Ladny JR, Rodriguez-Nunez A, Ruetzler K. A Novel Method of Newborn Chest Compression: A Randomized Crossover Simulation Study. Front Pediatr. 2018 May 29;6:159. doi: 10.3389/fped.2018.00159. eCollection 2018. — View Citation

Smereka J, Szarpak L, Smereka A, Leung S, Ruetzler K. Evaluation of new two-thumb chest compression technique for infant CPR performed by novice physicians. A randomized, crossover, manikin trial. Am J Emerg Med. 2017 Apr;35(4):604-609. doi: 10.1016/j.ajem.2016.12.045. Epub 2016 Dec 19. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	systolic blood pressure (SBP)	The manikin was connected with a fixed-volume arterial system attached to a monitor (Draeger Infinity® Delta; Draegerwerk AG & Co. KGaA, Luebeck, Germany) via an arterial pressure transducer (Edward Lifesciences: TruWave Disposable Pressure Transducer; Irvine, CA, USA). The arterial circuit composed of a 50-mL bag of normal saline solution (air removed) attached to the manikin chest plate and connected to the transducer with a 20-gauge intravenous catheter and tubing.	1 day
Secondary	diastolic blood pressure (DBP)	The manikin was connected with a fixed-volume arterial system attached to a monitor (Draeger Infinity® Delta; Draegerwerk AG & Co. KGaA, Luebeck, Germany) via an arterial pressure transducer (Edward Lifesciences: TruWave Disposable Pressure Transducer; Irvine, CA, USA). The arterial circuit composed of a 50-mL bag of normal saline solution (air removed) attached to the manikin chest plate and connected to the transducer with a 20-gauge intravenous catheter and tubing.	1 day
Secondary	mean arterial pressure (MAP)	The manikin was connected with a fixed-volume arterial system attached to a monitor (Draeger Infinity® Delta; Draegerwerk AG & Co. KGaA, Luebeck, Germany) via an arterial pressure transducer (Edward Lifesciences: TruWave Disposable Pressure Transducer; Irvine, CA, USA). The arterial circuit composed of a 50-mL bag of normal saline solution (air removed) attached to the manikin chest plate and connected to the transducer with a 20-gauge intravenous catheter and tubing.	1 day