Relationship Between Tissue Markes in Patients With Post Cardio Respiratory Syndrome

Cardiac Arrest Clinical Trial

Official title:

Relationship Between Lactate and Venous Oxygen Saturation Gradient of Carbon Dioxide in Patients With Post Cardio Respiratory Syndrome

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT01455662
• Other study ID #: 10086
• Status: Recruiting
• Phase: N/A
• First received: September 28, 2011
• Last updated: November 2, 2011
• Start date: January 2010
• Est. completion date: December 2011

Study information

• Verified date: November 2011
• Source: Hospital Nossa Senhora da Conceicao
• Contact: Vanessa M Oliveira, MD
• Phone: 05192513723
• Email: vanessa.oliveira480[@]gmail.com
• Is FDA regulated: No
• Health authority: Brazil: Ethics Committee
• Study type: Observational

Clinical Trial Summary

There is a correlation between hospital mortality and changes in markers of tissue perfusion, lactate, and venous oxygen saturation and carbon dioxide gradient.

Description:

Evaluation of the serum carbon dioxide gradient (GapCO2), central venous saturation (ScvO2) and the clearance of serum lactate (Clac) in predicting hospital mortality after cardiac arrest syndrome (post-PCR).

Prospective study, unicenter - Intensive Care Unit - HNSC. Period: May/2010 to June/2011. Serial assessment of GapCO2 of ScvO2 Clac and the first 72 hours post-PCR. Excluded under 18, survival of less than 6HS, pregnant women, traumatized, post-operative hypothermia and liver disease. T-student test, 95% (p <0.05).

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 100
• Est. completion date: December 2011
• Est. primary completion date: December 2011
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• All patients hospitalized in the intensive care unit after cardiopulmonary arrest with any pace

Exclusion Criteria:

pregnant women, traumatized, post-operative(less 7 days), hypothermia and liver disease.

• patients hospitalized in the intensive care unit with more than 6 hours post cardiac arrest

• less 18 years old

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Cardiac Arrest
• Heart Arrest

Locations

Country	Name	City	State
Brazil	Conceição Hospital	Porto Alegre	Rio Grande do Sul

Sponsors (1)

Lead Sponsor	Collaborator
Hospital Nossa Senhora da Conceicao

Country where clinical trial is conducted

Brazil, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	mortality		1 year	Yes
Secondary	correlation of clearance markers of perfusion with the use of vasopressor and positive fluid balance		6 hours	Yes