Cardiac Arrest Clinical Trial
Official title:
Assessment of Cardiopulmonary Resuscitation Quality During In-Hospital Cardiac Arrest
Using an investigational monitor/defibrillator that passively records CPR quality parameters, including chest compression rate and depth and ventilation rate and volume, we are prospectively recording CPR quality during sequential in-hospital cardiac arrests at the University of Chicago Hospitals. Using an audio feedback system linked to this device, we are studying whether such audio feedback improves CPR quality when provided to rescuers trained in the use of the device.
Patients who suffer cardiac arrest during their hospitalization at the University of Chicago
hospitals are given CPR and other resuscitation measures by trained physician and nurse
teams. This care is given with the use of defibrillators to monitor cardiac rhythm as well
as provide defibrillation as needed.
We have worked closely with engineers at Laerdal Medical Corporation to develop a
defibrillator that passively monitors the quality of CPR via additional external sensors
(see details in the following reference: Abella BS, Alvarado JP, Myklebust H, Edelson DP,
Barry A, O'Hearn N, Vanden Hoek TL, Becker LB. Quality of cardiopulmonary resuscitation
during in-hospital cardiac arrest. JAMA. 2005;293:305-10).
Patients who suffer in-hospital arrest are enrolled (provided they are over 16 years of age,
are not pregnant, and are not in the operating room or emergency room setting) with
mechanisms to satisfy IRB waiver of consent provisions. These patients receive the same care
as before the study, but CPR parameters are recorded by the device. In addition, the device
provides audio/visual "coaching" in CPR, based on the actual performance of CPR as measured.
We hypothesize that this coaching will improve CPR quality and hopefully improve survival
from cardiac arrest.
The first phase of investigation is now complete, where patients were enrolled and studied
without feedback ("baseline" group). Now we are enrolling patients into a second group with
feedback provided. Enrollment is nearly complete for this second group. We will then
evaluate the baseline and feedback groups to ascertain whether CPR improved over the two
cohorts.
;
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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