Sorafenib in Elderly mRCC

Status Completed

Clinical Trial Summary

This prospective, single arm, multi-center pilot study includes 120 mRCC patients over 65 years, no prior systemic treatment, determined to be candidates for systemic therapy by the investigator. The treatment with Sorafenib should comply with the recommendations written in the local product information. The primary endpoint is overall survival. The secondary endpoints including other effectiveness points, safety and patients characteristics. With 120 completed patients, if the observed survival rate at 12 months is 60%, the width of a 95% confidence interval will be approximately 18%.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01728948
Study type	Observational
Source	Bayer
Contact
Status	Completed
Phase	N/A
Start date	January 6, 2013
Completion date	January 16, 2017

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02248389` - Evaluation of a Laparoscopic High Intensity Focused Ultrasound Probe for the Ablation of Small Renal Masses	Phase 1
Completed	`NCT03900364` - a Prospective Trial Comparing Robot-assisted Partial Nephrectomy Versus Laparoscopic Partial Nephrectomy	N/A
Completed	`NCT00158782` - Study Of Safety And Tolerability Of GW786034 Given With Lapatinib In Cancer Patients	Phase 1
Completed	`NCT03109015` - Alternative Schedule Sunitinib in Metastatic Renal Cell Carcinoma: Cardiopulmonary Exercise Testing	Phase 2
Completed	`NCT00363194` - A Two-way Crossover Study Of The Effect Of Food On The Pharmacokinetics Of Pazopanib In Cancer Patients	Phase 1
Completed	`NCT01012011` - Regulatory Post Marketing Surveillance Study on Nexavar®	N/A
Completed	`NCT00842790` - Impact of Predicting Anti-angiogenic Response in mRCC Using Functional Imaging	N/A
Completed	`NCT00529802` - Exploratory Study Evaluating Fluorodeoxyglucose - Position Emission Tomography as a Predictive Marker for Therapy With RAD001 in Metastatic Renal Cell Cancer	Phase 2
Completed	`NCT00338884` - Safety And Effectiveness Of Daily Dosing With 37.5 mg Sunitinib Malate In Patients With Advanced Kidney Cancer	Phase 2
Completed	`NCT00356460` - Safety and Efficacy Study of GC1008 to Treat Renal Cell Carcinoma or Malignant Melanoma	Phase 1
Completed	`NCT00387764` - Extension Study to VEG105192 to Assess Pazopanib in Patients With Advanced/Metastatic Renal Cell Cancer	Phase 3
Completed	`NCT00095186` - Safety/Efficacy Study of Oral Recombinant Human Lactoferrin in Renal Cell Carcinoma	Phase 2
Completed	`NCT00079612` - Study of Nexavar (Sorafenib, BAY 43-9006) in Patients With Advanced Refractory Cancer	Phase 2
Completed	`NCT00043368` - PF-3512676 (CPG 7909) Injection For Patients Who Completed An Oncology Study Using PF-3512676 (CPG 7909)	Phase 2
Active, not recruiting	`NCT04489771` - A Study of Belzutifan (MK-6482) in Participants With Advanced Renal Cell Carcinoma (MK-6482-013)	Phase 2
Completed	`NCT00516672` - Phase I Study of Pazopanib Alone and In Combination With Lapatinib in Japanese Patients With Solid Tumors	Phase 1
Withdrawn	`NCT05104905` - A Phase I/II Open Label Single Centre Trial to Assess the Safety, Tolerability and Efficacy of Single Dose Neoadjuvant Anti-CLEVER-1 Antibody Bexmarilimab in Localised Renal Cell and Colon Carcinoma	Phase 1/Phase 2
Terminated	`NCT03685591` - PF-06952229 Treatment in Adult Patients With Advanced Solid Tumors	Phase 1
Withdrawn	`NCT03111901` - Low-dose Interleukin-2 and Pembrolizumab in Melanoma and Renal Cell Cancer	Phase 1/Phase 2
Recruiting	`NCT05544929` - A Study of Safety and Efficacy of KFA115 Alone and in Combination With Pembrolizumab in Patients With Select Advanced Cancers	Phase 1