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Combination of Regorafenib and Nivolumab in Unresectable Hepatocellular Carcinoma — RENOBATE  

Carcinoma, Hepatocellular Clinical Trial

Official title:
Phase II Study of Regorafenib-nivolumab Combination Therapy for Chemotherapy-naïve Patients With Unresectable or Metastatic Hepatocellular Carcinoma

Clinical Trial Summary

Regorafenib and nivolumab are proven effective agents for the management of unresectable hepatocellular carcinoma patients. As preclinical studies have suggested potential synergism between antiangiogenic agents and immune checkpoint inhibitors, regorafenib and nivolumab may have synergism in terms of efficacy. Herein, this study investigates the combination of regorafenib and nivolumab as first-line therapy in patients with unresectable hepatocellular carcinoma.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04310709
Study type Interventional
Source Asan Medical Center
Contact
Status Completed
Phase Phase 2
Start date June 16, 2020
Completion date November 30, 2022
View Details
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