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Dose Escalation Study for Primary Hepatocellular Carcinoma — SBF-HCC  

Carcinoma, Hepatocellular Clinical Trial

Official title:
Multi-institution Phase I/II Dose Escalation Study of Hypofractionated Stereotactic Body Radiation Therapy for Primary Hepatocellular Carcinoma

Clinical Trial Summary

The purpose of this study is to determine the maximum tolerated dose of limited fractions of large dose radiation in an effort to achieve a biologically potent cancer therapy in selected patients with primary hepatocellular carcinoma.

Clinical Trial Description

Despite recent advances in early detection and diagnosis, only 30-40% of patients with hepatocellular carcinoma may benefit from radical therapies. Liver transplantation offers the best chance for cure. Surgical resection has been the only other potentially curative option, but the majority of patients are not candidates for resection. This reflects the usual comorbidity of severe underlying liver disease that either precludes surgery or makes the surgical approach extremely dangerous. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00243841
Study type Interventional
Source Indiana University
Contact
Status Completed
Phase N/A
Start date May 2004
Completion date December 31, 2016
View Details
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