Debulking Effect of Curretage on Basal Cell Carcinomas - a Histological Assessment.

Carcinoma, Basal Cell Clinical Trial

Official title:

Relation of Basal Cell Carcinoma Tumour Thickness, Histologically Estimated, in Punch Biopsies Performed Before and After Curretage.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00237107
• Other study ID #: EC-003
• Status: Completed
• Phase: N/A
• First received: October 10, 2005
• Last updated: July 18, 2016
• Start date: April 2002
• Est. completion date: December 2004

Study information

• Verified date: July 2016
• Source: Norwegian University of Science and Technology
• Contact: n/a
• Is FDA regulated: No
• Health authority: Norway:National Committee for Medical and Health Research Ethics
• Study type: Interventional

Clinical Trial Summary

The aim of this study was to compare histologically observed tumour infitration of basal cell carcinoma (bcc) lesions before and after curretage.A significant reduction of tumour depth would enable further bcc's included for superficial non-invasive treatment modalities such as topical photodynamic therapy.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 36
• Est. completion date: December 2004
• Est. primary completion date: December 2004
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• bcc with tumour depth two mm.or more

Exclusion Criteria:

• bcc tumours smaller than three mm in mean diameter.

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label

Related Conditions & MeSH terms

• Carcinoma
• Carcinoma, Basal Cell

Intervention

Procedure:
• Curretage

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Norwegian University of Science and Technology

References & Publications (1)

Christensen E, Mørk C, Foss OA. Pre-treatment deep curettage can significantly reduce tumour thickness in thick Basal cell carcinoma while maintaining a favourable cosmetic outcome when used in combination with topical photodynamic therapy. J Skin Cancer. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Reduction of tumour thickness 0,5mm or more after curretage		1 hour	No
Secondary	Comparison of tumour thickness in punch biopsies performed on referral, before and after curretage.		3 months	No