Head and Neck Neoplasms Clinical Trial
Official title:
A Phase I/IIB Study of Combination Weekly Carboplatin, Cetuximab and Dose Escalation of RAD001 in Recurrent Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN)
The purpose of this study is to test the drug RAD001 in combination with other chemotherapy
drugs, Carboplatin and Cetuximab. Because RAD001 has not been used in this combination
before, it is not clear which dose will be best when used in combination.
The investigators will test the safety of RAD001 in combination with Carboplatin and
Cetuximab and see what effects (good and/or bad) it has on your cancer, and find the highest
dose of RAD001 that can be given without causing bad side effects. The doses of Carboplatin
and Cetuximab will not be varied as both these drugs are considered to be part of the
current standard of care for patients with your condition.
n/a
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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